Risk factors for bleeding complications in percutaneous renal biopsy

Abstract

For those who are clinically suspected of having amyloidosis or hypertension, more careful biopsy procedures and observations are necessary.

The Incidence of Major Hemorrhagic Complications After Renal Biopsies in Patients with Monoclonal Gammopathies

“…This is comparable to previous work, where major hemorrhagic complication rates after native renal biopsies were reported as ranging from 1 to 8% (15,(17)(18)(19)(20)(21). This study included 148 patients with a known monoclonal gammopathy.…”

“…A few studies have analyzed the bleeding risk associated specifically with amyloidosis. Eiro et al (20) found a higher rate of bleeding (defined as drop in hemoglobin by Ͼ1 g/dl) in patients with amyloidosis compared with other histologic findings, although this considered just four patients with the diagnosis. Conversely, Soares et al (15) found 4% of 101 patients with amyloidosis developed a major hemorrhagic complication; this was not significantly greater than the control group.…”

“…Numerous studies have investigated the potential risk factors for complications after percutaneous renal biopsy (17)(18)(19)(20). Although monoclonal gammopathy-associated disease has been suggested to confer an increased risk of hemorrhagic complications (8,9), the current evidence supporting this theory is sparse.…”

“…With this limitation, it was not possible to identify cases where there were minor hemorrhagic complications. Previous work has indicated that a high proportion of patients will acquire a small hematoma after a renal biopsy, whatever the underlying diagnosis (20,25). However, these are unlikely to be of clinical significance, and it can be argued that their detection is unnecessary.…”

Preeclampsia before 20 weeks of gestation: a case report and review of the literature

“…Generally, in pregnant women with new onset of hypertension, aggressive blood pressure reduction could be harmful for the fetus and a reasonable goal is recommended to be systolic pressure between 140 and 160 mmHg and diastolic pressure between 90 and 100 mmHg by Japan Society for the Study of hypertension in pregnancy. On the other hand, increased blood pressure (systolic pressure [140 mmHg or diastolic pressure [90 mmHg) was an independent predictor of post-biopsy bleeding complications [21]. Therefore, we considered this patient at higher risk for biopsy-related bleeding.…”