Risk factors for bone flap resorption after autologous bone cranioplasty

Abstract

Background: One of the most common complications following autologous cranioplasty is bone flap resorption (BFR). Severe BFR can lead to revision surgery with implantation of synthetic bone flap and also necessarily lead to higher hospital expenses. This study aims to perform a meta-analysis to summarize available evidence regarding risk factors of BFR requiring a second surgery in patients with autologous cranioplasty. Methods: Cohort, case-control, and cross-sectional studies that report the incidence and risk factors of BFR among patients with autologous cranioplasty, published in English, will be considered for selection. Three databases from inception to May 2020 will be searched. The process of data selection, quality assessment, and data extraction will be assessed by 2 authors independently. The study quality will be assessed by Newcastle-Ottawa Scale (NOS) and Agency for Healthcare Research and Quality checklist. The statistical analysis of this meta-analysis will be calculated by Review manager version 5.3. Results: The results of this systematic review and meta-analysis will be disseminated through academic conferences and expected to publish in a peer-reviewed journal Conclusion: This study will offer high-quality evidence about risk factors for BFR after autologous cranioplasty. Registration number: INPLASY202050063.

Association between developmental defects of enamel and early childhood caries in children under 6 years old: A systematic review and meta-analysis

“…2016 [ 38 ] Australia ★★ ★★ 4 Poor Paixão-Gonçalves et al. 2019 [ 8 ] Brazil ★★★ ★★ ★★★ 8 Good a Quality assessment: Good quality (7–9 stars), fair quality (5–6 stars) and poor quality (0–4 stars) as classified on previous studies [ 32 , 33 ]. …”

“… a Quality assessment: Good quality (7–9 stars), fair quality (5–6 stars) and poor quality (0–4 stars) as classified on previous studies [ 32 , 33 ]. …”

“…Evaluation of the quality of the studies included according to the Newcastle-Ottawa Scale (NOS). a Quality assessment: Good quality (7-9 stars), fair quality (5-6 stars) and poor quality (0-4 stars) as classified on previous studies [32,33].…”

“…To determine the level of quality of each included study, results were converted to good, fair, and poor quality based on previous studies [ 32 , 33 ] as follows: Good quality: 7–9 stars Fair quality: 5–6 stars Poor quality: 0–4 stars …”

Customized alloplastic cranioplasty of large bone defects by 3D-printed prefabricated mold template after posttraumatic decompressive craniectomy: A technical note

“…[25] Cranioplasty with an autologous bone flap after decompressive craniectomy has been the preferable treatment for cranial reconstruction. [21] Since partial aseptic bone resorption is a common physiological phenomenon during the bone revitalization process, [29] such a procedure is frequently burdened by bone flap insufficient reintegration, [14,22,49] and the increased risk of infective complications. Alternatively, when alloplastic cranioplasty is concerned, manual shaping of the bone cement (alloplastic material) is challenging and time consuming and may not always lead to a satisfactory result.…”