Risk Factors for Chronic and Recurrent Otitis Media–A Meta-Analysis

Zhang, Yan; Xu, Min; Zhang, Jin; Zeng, Lingxia; Wang, Yanfei; Zheng, Qing Yin

doi:10.1371/journal.pone.0086397

Cited by 137 publications

(164 citation statements)

References 64 publications

(67 reference statements)

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“…The influence of gender is controversial with some studies showing a higher prevalence in males [10,11], other studies in females [7], and the remainder failing to show an effect of gender on otitis media [4,5,8]. Our results showed that males were found to undergo tympanostomy tube insertion slightly more than females (55.1, 95% CI 49.1-61.0 vs. 44.9, 95% CI 39.0-50.9, respectively).…”

Section: Discussionmentioning

confidence: 99%

“…A few studies have shown a statistically significant influence on the presence of otitis media [2,4], while others have failed to identify a relationship [5,11]. The likelihood that a child in the 8-12 year-old cohort had siblings in the home was increased compared to those in the younger group (OR 1.72, p = 0.03).…”

Section: Discussionmentioning

confidence: 99%

“…Upper respiratory tract infections (URTIs) have been universally identified as a significant prognostic factor for COM/ROM [5][6][7][8]. Studies have shown that the opening and closing function of the eustachian tube (ET) [13], as well as the extent of inflammation on ET mucosa [14] are affected by URTIs.…”

Section: Discussionmentioning

confidence: 99%

“…An extensive literature review was conducted to identify risk factors for COM/ROM with a particular focus on those studies in school-age children [3][4][5][6][7][8][9][10][11][12]. Based on this information, a data collection form with pertinent factors relating to demographics, social environment, and patient history was developed.…”

Section: Methodsmentioning

confidence: 99%

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Risk Factors for Refractory and Delayed De Novo Otitis Media Requiring Pressure Equalization Tube Insertion

Bowe¹,

Vargo²,

Abramoff³

et al. 2014

Otolaryngol.--head neck surg.

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Objective-Limited data exists regarding risk factors for otitis media in older children and specifically those for which surgical intervention is performed. This study investigated potential risk factors in this older age group who required pressure equalization tube (PET) insertion. Study design-Retrospective cohort study Setting-Tertiary care pediatric academic medical centerSubjects and methods-Children 6-12 years old undergoing PET insertion between October 1, 2010 and September 30, 2011. Data was stratified into two separate age cohorts (6-7 versus 8-12-year-olds) and compared using chi-square analysis.Results-A total of 263 patients met study criteria. PET insertion was most common in 6 yearolds (36%, 95/263). Presence of siblings (p=0.03) and history of recurrent upper respiratory tract infection (p<0.01), otalgia (p<0.05), otorrhea (p<0.001), and nasal discharge (p<0.001) were common in the older cohort. No statistical difference was found for history of recurrent acute otitis media, allergy, asthma, or atopy between the two groups (p=0.23-0.92), although the overall prevalence of these conditions was high in both cohorts. Conclusion-The 8-12-year-olds had a history of recurrent upper respiratory tract infection and more infectious symptoms than the 6-7-year-olds. Atopy can lead to a heightened susceptibility to upper respiratory tract infections and potential increase in the relative risk of otitis media. In our patient population, while there was no statistically significant difference in history of asthma, allergy, or atopy, the overall prevalence within both cohorts was relatively high. Therefore, this This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Risk Factors for Refractory and Delayed De Novo Otitis Media Requiring Pressure Equalization Tube Insertion

Bowe¹,

Vargo²,

Abramoff³

et al. 2014

Otolaryngol.--head neck surg.

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“…20 telah melaporkan bahwa dari berbagai faktor risiko yang ada, alergi atau keadaan atopi merupakan salah satu faktor risiko yang dapat meningkatkan otitis media kronik (p<0,001; OR=1,36). Bozkus dkk.…”

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Hubungan Rinitis Alergi dengan Kejadian Otitis Media Supuratif Kronik

Diana¹,

Haryuna²

2017

mkb

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AbstrakOtitis media supuratif kronik (OMSK) merupakan infeksi telinga tengah yang berat, tidak hanya terjadi di negara berkembang, tetapi juga di negara maju. Prevalensi OMSK di dunia melibatkan 65-330 juta penduduk. Terdapat beberapa teori yang mengungkapkan peran rinitis alergi dalam terjadinya OMSK, teori yang paling banyak digunakan adalah disfungsi tuba eustachius. Penelitian ini merupakan penelitian analitik dengan pendekatan kasus-kontrol tanpa berpasangan. Pengambilan sampel dengan metode consecutive sampling sebanyak 80 responden yang terdiri atas 40 responden OMSK dan 40 responden non-OMSK yang datang ke Poliklinik THT RSUP H. Adam Malik Medan pada bulan Agustus-Oktober 2014. Seluruh responden dilakukan anamnesis, pemeriksaan telinga dan hidung, serta mengisi kuesioner Score for Allergic Rhinitis (SFAR). Hasil penelitian menunjukkan bahwa pada kelompok OMSK, 28 orang (70%) menderita rinitis alergi dan 12 orang (30%) tidak menderita rinitis alergi. Pada kelompok non-OMSK 6 orang (15%) menderita rinitis alergi dan 34 orang (85%) tidak menderita rinitis alergi. Terdapat hubungan yang signifikan antara rinitis alergi dan kejadian OMSK (p<0,001). Pasien rinitis alergi memiliki risiko 13 kali lebih besar untuk menderita OMSK dibanding dengan pasien tanpa rinitis alergi (OR=13,222; 95% IK=4, 732 Relationship between Allergic Rhinitis and Incidence of Chronic Suppurative Otitis Media AbstractChronic suppurative otitis media (CSOM) is a severe infection of the middle ear that is seen not only in developing countries but also in industrialized countries. The prevalence of CSOM in the world involves 65-330 million people. There are some theories regarding the role of allergic rhinitis in CSOM patients with eustachian tube dysfunction theory as the most widely used theory. This was a non-matched case control analytical study on 80 respondents, 40 CSOM respondents and 40 non-CSOM respondents, who were sampled using consecutive sampling method at the Ear-Nose-Throat (ENT) clinic of H. Adam Malik General Hospital in August-October 2014. Anamnesis as well as ear and nose examinations were performed and all respondents fill out the Score For Allergic Rhinitis (SFAR) questionnaire. The results showed that in CSOM group, 28 people (70%) suffered from allergic rhinitis and 12 people (30%) did not suffer from allergic rhinitis. In non-CSOM group, the numbers were 6 people (15%) and 34 (85%), respectively. There was a significant relationship between allergic rhinitis and the incidence of CSOM (p<0.001). Allergic rhinitis patients have a 13 times greater risk to suffer CSOM than patients without allergic rhinitis (OR=13.222, 95% CI=4.400-39.732). The probability of patients with allergic rhinitis to suffer CSOM is 92.9%. In conclusion, there is a relationship between allergic rhinitis and the incidence of CSOM. [MKB. 2017;49(2):79-85]

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Association Between Social Disadvantage and Otitis Media Treatment in US Children With Commercial Insurance

Qian

Rehkopf

2023

JAMA Otolaryngol Head Neck Surg

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ImportanceIt is well established that social disadvantage is associated with earlier, more frequent, and more severe otitis media in children. Appropriate medical and surgical treatment of otitis media can prevent hearing loss and other complications, which may affect future academic and employment opportunities in socially disadvantaged populations. Clinical treatment patterns for otitis media in the US are unclear.ObjectiveTo describe and quantify social disparities in the treatment patterns of otitis media in children in the US.Design, Setting, and ParticipantsThis cross-sectional study included claims data from the Optum Clinformatics Data Mart Database between January 1, 2003, and March 31, 2021, with linked inpatient, outpatient, and pharmaceutical claims for 4 831 408 children with otitis media.ExposuresAge at first otitis media diagnosis, sex, environmental allergies, gastroesophageal reflux, adenotonsillar hyperplasia, zip code, social deprivation index score, social vulnerability index score.Main Outcomes and MeasuresTreatment of recurrent and suppurative otitis media in children, insertion of tympanostomy tubes, and treatment for severe complications of undertreated otitis media. The principal measure of social disadvantage was the social deprivation index. The social vulnerability index was used for sensitivity analyses to ensure external validity. Multiple logistic regression analyses were used to quantify the association of all projected variables with the study outcomes.ResultsAmong 4 831 408 US children with otitis media (median [IQR] age, 4 [1-8] years; 2 491 557 boys [51.57%]), 994 921 (20.59%) were treated for recurrent otitis media, 717 978 (14.86%) were treated for suppurative otitis media, 335 949 (6.95%) received tympanostomy tubes, and 10 975 (0.23%) had severe complications of otitis media. In multivariable regression models including patient factors and social indices, earlier age at diagnosis, male sex, environmental allergies, gastroesophageal reflux, and adenotonsillar hyperplasia were associated with increased treatment for otitis media, whereas social deprivation index was associated with lower odds of medical treatment for recurrent otitis media (odds ratio [OR], 0.86; 95% CI, 0.85-0.87), suppurative otitis media (OR, 0.61; 95% CI, 0.60-0.62), and insertion of tympanostomy tubes (OR, 0.76; 95% CI, 0.75-0.78) but higher odds of having severe complications (OR, 1.28; 95% CI, 1.19-1.37).Conclusions and RelevanceThe findings of this cross-sectional study suggest that children with otitis media who were socially disadvantaged were less likely to receive treatment and more likely to experience complications for undertreated otitis media. As otitis media is a modifiable risk factor for hearing loss, efforts need to be made to ensure equitable access to treatment for all children.

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Risk Factors for Chronic and Recurrent Otitis Media–A Meta-Analysis

Cited by 137 publications

References 64 publications

Risk Factors for Refractory and Delayed De Novo Otitis Media Requiring Pressure Equalization Tube Insertion

Risk Factors for Refractory and Delayed De Novo Otitis Media Requiring Pressure Equalization Tube Insertion

Hubungan Rinitis Alergi dengan Kejadian Otitis Media Supuratif Kronik

Association Between Social Disadvantage and Otitis Media Treatment in US Children With Commercial Insurance

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