Risk Factors for Early Hemorrhagic and Thrombotic Complications After Kidney Transplantation

Pawlicki, Jacek; Cierpka, Lech; Król, Robert; Ziaja, Jacek

doi:10.1016/j.transproceed.2011.07.018

Cited by 25 publications

(33 citation statements)

References 14 publications

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“…We identified a 1.1% incidence of early TEC and 4.4% bleeding complications. This is lower than reported in the literature . High BMI and multiple donor arteries were associated with increased risk for TEC.…”

Section: Discussioncontrasting

confidence: 62%

“…Pawlicki et al . reported an association between increased risk for bleeding and antithrombotic prophylaxis, but this study was limited by sample size ( n = 67), and suboptimal methodology: hematomas of ≥4 cm, with or without graft compression were scored as bleeding events. In general, hematomas of ≥4 cm are common after KTx and rarely have any clinical relevance.…”

Section: Discussionmentioning

confidence: 99%

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Perioperative antithrombotic therapy does not increase the incidence of early postoperative thromboembolic complications and bleeding in kidney transplantation – a retrospective study

et al. 2019

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SummaryPerioperative antithrombotic therapy could play a role in preventing thromboembolic complications (TEC) after kidney transplantation (KTx), but little is known on postoperative bleeding risks. This retrospective analysis comprises 2000 single‐organ KTx recipients transplanted between 2011 and 2016 in the two largest transplant centers of the Netherlands. TEC and bleeding events were scored ≤7 days post‐KTx. Primary analyses were for associations of antithrombotic therapy with incidence of TEC and bleeding. Secondary analyses were for associations of other potential risk factors. Mean age was 55 ± 14 years, 59% was male and 60% received a living donor kidney. Twenty‐one patients (1.1%) had a TEC. Multiple donor arteries [OR 2.79 (1.15–6.79)] and obesity [OR 2.85 (1.19–6.82)] were identified as potential risk factors for TEC. Bleeding occurred in 88 patients (4.4%) and incidence varied significantly between different antithrombotic therapies (P = 0.006). Cardiovascular disease [OR 2.01 (1.18–3.42)], pre‐emptive KTx [OR 2.23 (1.28–3.89)], postoperative heparin infusion [OR 1.69 (1.00–2.85)], and vitamin K antagonists [OR 6.60 (2.95–14.77)] were associated with an increased bleeding risk. Intraoperative heparin and antiplatelet therapy were not associated with increased bleeding risk. These regimens appear to be safe for the possible prevention of TEC without increasing the risk for bleeding after KTx.

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Section: Discussioncontrasting

confidence: 62%

Section: Discussionmentioning

confidence: 99%

Perioperative antithrombotic therapy does not increase the incidence of early postoperative thromboembolic complications and bleeding in kidney transplantation – a retrospective study

et al. 2019

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“…Ją sukelia cukrinis diabetas, glomerulonefritai, pirminė ar antrinė hipertenzija, policistinės inkstų ligos, intersticiniai nefritai, inkstų akmenligė, pielonefritas, paveldimos ir kitos ligos [1]. Transplantacija -svarbus etapas ligonių gyvenime, o ankstyvas periodas pavojingas dėl rimtų komplikacijų (kraujavimo, inksto arterijos susiaurėjimo ir trombozės, hematurijos, atmetimo reakcijų, žaizdų supūliavimo ir virusinės infekcijos, kitų), todėl būtina laiku pastebėti komplikacijas ir užtikrinti ligonio bei transplantuoto inksto optimalią slaugą [2]. Slaugytojos dalyvavimas šiame procese nagrinėjamas retai, tačiau yra svarbus, nes gali užkirsti kelią komplikacijų atsiradimui ir progresavimui [3].…”

Section: įVadasunclassified

“…2 inkstai buvo persodinti iš giminingo donoro (sutuoktinio ir motinos), likusieji -iš kadaverinių donorų. Pagrindinės galutinės stadijos inkstų ligų priežastys šiems ligoniams: glomerulonefritas (6), cukrinis diabetas (3, 1 iš jų -inksto ir kasos komplekso), hipertenzija (3), inkstų policistozė (2 Pirmasis skaičius rodo pacientų skaičių, kuriems sutrikimas/norma nustatyta 1 parą, antrasis -7 parą; * -p < 0,05. ''-" -''nevertinta/priklausoma būklė".…”

Section: Rezultataiunclassified

Pacientų Gyvybinių Veiklų Vertinimas Ir Komplikacijų Prevencijos Būdai Ankstyvuoju Periodu Po Inksto Transplantacijos

Čergelytė

Gerikienė

Rimševičius

et al. 2014

Medicinos Teorija Ir Praktika

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“…Unfortunately, complete improvement in hemostasis does not occur after successful renal transplantation. 7 A previous study by Mathis et al 2 evaluated bleeding events due to therapeutic IV heparin in renal transplant patients to prevent perioperative thrombosis. They found no link between the immunosuppressive agents used in the study (primary agents: cyclosporine, mycophenolate, prednisone; alternatives: tacrolimus and rapamycin) and risk of bleeding.…”

mentioning

confidence: 99%

Evaluation of Bleeding Rates in Renal Transplant Patients on Therapeutic Intravenous Heparin

Ringenberg¹,

Desanto

Opsha

et al. 2013

Hosp Pharm

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Risk Factors for Early Hemorrhagic and Thrombotic Complications After Kidney Transplantation

Cited by 25 publications

References 14 publications

Perioperative antithrombotic therapy does not increase the incidence of early postoperative thromboembolic complications and bleeding in kidney transplantation – a retrospective study

Perioperative antithrombotic therapy does not increase the incidence of early postoperative thromboembolic complications and bleeding in kidney transplantation – a retrospective study

Pacientų Gyvybinių Veiklų Vertinimas Ir Komplikacijų Prevencijos Būdai Ankstyvuoju Periodu Po Inksto Transplantacijos

Evaluation of Bleeding Rates in Renal Transplant Patients on Therapeutic Intravenous Heparin

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