Risk factors for failure of supraglottoplasty

Predictors of Intensive Care Unit Stay After Pediatric Supraglottoplasty

“…We did not identify any effect of comorbidity on immediate outcomes after supraglottoplasty. The effect of comorbidity on outcomes after supraglottoplasty is somewhat controversial, with most reports suggesting that patients with comorbid conditions such as congenital syndromes or neurologic or pulmonary disease have poorer long-term outcomes, 15,16 although a series by Day et al 17 in 2012 suggested no effect. Our data suggest that these patients are at similar risk to the general population in terms of immediate postoperative complications.…”

Objective Outcomes of Supraglottoplasty for Children With Laryngomalacia and Obstructive Sleep Apnea

“…The presence of synchronous airway lesions; associated congenital anomalies; neurologic, cardiac, or other medical comorbidities (ie, GERD); and prematurity or younger age variably portends a worse prognosis than patients with isolated laryngomalacia. 8,28,29 The mechanisms behind supraglottoplasty failure are not well understood, and there may not be a one-size-fits-all explanation given the multifactorial contributions of patients. Despite the heterogeneous populations pooled for our metaanalysis (different age groups, syndromic and neurologically comorbid patients), statistical significance was achieved for all but 1 polysomnography parameter.…”

Supraglottoplasty for laryngomalacia with obstructive sleep apnea: A systematic review and meta‐analysis

“…Forty‐four studies were excluded for the following reasons: the number of patients undergoing polysomnography pre‐ and postsupraglottoplasty was not provided; no quantitative data for polysomnograms was provided; only adults were included; procedure(s) were performed in addition to the supraglottoplasty with no stratification of data for those who underwent isolated supraglottplasty; only preoperative data was available; some children were sedated with choral hydrate; the postoperative data was only available for a fraction of patients; portable pulse‐oximetry was used instead of formal polysomnography; or they were review articles …”

“…Forty-four studies were excluded for the following reasons: the number of patients undergoing polysomnography pre-and postsupraglottoplasty was not provided 43 ; no quantitative data for polysomnograms was provided 12,18,21,22,[24][25][26]28,29,[32][33][34][35][36][37][38][39]41,42,[44][45][46]49,51,53,54,56,58,61,64,66 ; only adults were included 19 ; procedure(s) were performed in addition to the supraglottoplasty with no stratification of data for those who underwent isolated supraglottplasty 27,50,63 ; only preoperative data was available 55 ; some children were sedated with choral hydrate 47 ; the postoperative data was only available for a fraction of patients 30 ; portable pulse-oximetry was used instead of formal polysomnography 31 ; or they were review articles. 40,52,62 Overall, there were a total of 138 patients (ages 1 month-12.6 years) with quantitative polysomnographic data who underwent isolated supraglottoplasty.…”