Risk factors for gastroesophageal reflux disease: a population-based study

Sadafi, Sepehr; Azizi, Ali; Pasdar, Yahya; Shakiba, Ebrahim; Darbandi, Mitra

doi:10.1186/s12876-024-03143-9

Cited by 9 publications

(1 citation statement)

References 42 publications

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“…Multiple studies identi ed smoking as a risk factor for GERD. 75,78,96,98,113 Kim, Jang, et al interestingly found that former smoking was signi cantly associated with risk of GERD, while current smoking was not signi cantly associated. 83 When investigating gender-speci c differences on the effects of smoking on the risk of GERD, Kim, Jung, et al found that smoking increased risks in both men and women.…”

Section: Methodsmentioning

confidence: 99%

Gastroesophageal Disease and Environmental Exposure: A Systematic Review

Kim,

Podury,

Zadeh

et al. 2024

Preprint

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Environmental exposure-associated disease is an active area of study, especially in the context of increasing global air pollution and use of inhalants. Our group is dedicated to the study of exposure-related inflammation and downstream health effects. While many studies have focused on the impact of inhalants on respiratory sequelae, there is growing evidence of the involvement of other systems including autoimmune, endocrine, and gastrointestinal. This systematic review aims to provide a recent update that will underscore the associations between inhalation exposures and upper gastrointestinal disease in the contexts of our evolving environmental exposures. Keywords focused on inhalational exposures and gastrointestinal disease. Primary search identified n = 764 studies, of which n = 64 met eligibility criteria. In particular, there was support for existing evidence that PM increases the risk of upper gastrointestinal diseases. Smoking was also confirmed to be major risk factor. Interestingly, studies in this review have also identified waterpipe use as a significant risk factor for gastroesophageal reflux and gastric cancer. Our systematic review identified inhalational exposures as risk factors for aerodigestive disease, further supporting the association between environmental exposure and digestive disease. However, due to limitations on our review’s scope, further studies must be done to better understand this interaction.

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Section: Methodsmentioning

confidence: 99%

Gastroesophageal Disease and Environmental Exposure: A Systematic Review

Kim,

Podury,

Zadeh

et al. 2024

Preprint

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A cross-sectional study of physical activity and chronic diseases among middle-aged and elderly in China

Huang,

2024

Sci Rep

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Regular physical activity is beneficial for both physical and mental health. However, studies on physical activity levels among middle-aged and elderly individuals in China are relatively scarce, and the association between different activity levels and certain chronic diseases remains unclear. Using cross-sectional data from the 2020 China Health and Retirement Longitudinal Study (CHARLS), this study describes the prevalence of chronic diseases and examines their associations with physical activity (PA). Participants self-reported the presence of fifteen chronic health conditions: hypertension, dyslipidemia, diabetes, cancer, chronic lung diseases, liver disease, heart attack, stroke, kidney disease, stomach diseases, emotional and mental issues, memory-related diseases, Parkinson’s disease, arthritis or rheumatism, and asthma. Total physical activity was assessed through self-reports using instruments similar to the International Physical Activity Questionnaire (IPAQ). Multivariate logistic regression was used to estimate the association between chronic diseases and PA. In China, more than one-sixth of middle-aged and elderly individuals do not meet physical activity guidelines. Compared to those with low PA, individuals with moderate PA were associated with a lower prevalence of four chronic diseases (heart disease, stroke, emotional and mental issues, asthma), while those with high PA were associated with a lower prevalence of nine chronic diseases (hypertension, dyslipidemia, diabetes, cancer, heart attack, stroke, emotional and mental issues, memory-related diseases, asthma). Higher physical activity levels are associated with lower odds of chronic diseases. These associations between physical activity and various chronic diseases are inconsistent. Future research should employ cohort or experimental studies to determine the causal relationships between physical activity and the prevalence of different chronic diseases.

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