Risk factors for infection of the diabetic foot with multi-antibiotic resistant microorganisms

Aerobic bacterial profile and antibiotic resistance in patients with diabetic foot infections

“…Our study showed that MDROs were common in hospitalized patients with chronic and acute wounds. An increase in the occurrence of chronic wound infections with MDROs in the diabetes mellitus population has been noted over the last decade and has been primarily attributed to MRSA, but antibioticresistant Gram-negative organisms, particularly Pseudomonas aeruginosa, have also been implicated (4) (29) . In our study, few patients underwent some type of amputation.…”

“…Approximately one-fourth of people with diabetes will develop an ulcer during their lifetime, and as many as half of these ulcers will become infected (2) (3) . In people with diabetes and foot ulcers, several factors, such as inappropriate antibiotic treatment, the chronic nature of the wound, and frequent hospital admission, can infl uence the presence of multidrug-resistant microorganisms in the ulcer (4) . Moreover, the specifi c organisms identifi ed in diabetic foot infections can differ not only from patient to patient and hospital to hospital but also from one part of the country to another (5) .…”

Increasing incidence of Gram-negative organisms in bacterial agents isolated from diabetic foot ulcers

“…In the current study, carbapenem sensitivity was 49.4% and multidrug resistant strains represented almost one third of all Pseudomonas species. Shankar et al [8] from South India and Kandemir et al [19] from Turkey reported 44% and 45% rates for multidrug resistant P. aeruginosa strains isolated from patients with DFIs, respectively. Kandemir et al [19] demonstrated that risk factors such as the duration of past antibiotic use, prolonged hospitalization, and the presence of neuroischemic diabetic foot ulcers and osteomyelitis were closely associated with multiple drug resistance.…”

Vacuum Sealing Drainage Treatment of Multi-Drug–Resistant Enterobacter Cloacae Wound Infection in a Diabetic Patient: A Case Report and Review of the Literature

“…Diabetic foot ulcers are induced by not only necrosis of the deep tissues due to neurological or vascular disease of the lower limbs but also wound infection [3]. Long-term hyperglycemia alters the microcirculation, which impedes wound healing [4]. Such ulcers are vulnerable to infections.…”