Risk Factors for Intracerebral Hemorrhage in the General Population

Ariesen, M.J.; Claus, Steven; Rinkel, Gabriël J.E.; Algra, Ale

doi:10.1161/01.str.0000080678.09344.8d

Cited by 674 publications

(518 citation statements)

References 37 publications

Supporting

Mentioning

453

Contrasting

Unclassified

Order By: Relevance

“…A meta-analysis performed in 2003 showed that the main risk factors for ICH were male gender, age, hypertension and alcohol intake. High cholesterol levels seem to be a protective factor against HS, but individuals with this condition are more prone to develop IS 22 . Our fi ndings showed that hypertension was the main risk factor for stroke.…”

Section: Discussionmentioning

confidence: 99%

Frequency of stroke types at an emergency hospital in Natal, Brazil

Martins

Figueiredo

Rocha

et al. 2007

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

-We performed a cross-sectional study of stroke type frequency at a local emergency hospital, in Natal, Brazil. The sample consisted of all patients who were admitted to an emergency hospital with a presumptive diagnosis of stroke. Of the 416 patients, 328 were studied, 88 were excluded for not meeting inclusion criteria, 74.7% (n= 245) had ischemic stroke 17.7% (n=58) had intracerebral hemorrhage, 7.6% (n=25) had subarachnoid hemorrhage; 173 were men (52.7%). Mean age was 64.1 years. The intrahospital mortality rate was 10.2%, 17.2% and 36% for ischemic stroke, intracerebral hemorrhage and subarachnoid hemorrhage, respectively. The most prevalent modifiable risk factor was hypertension for ischemic stroke (67.6%) and hemorrhage stroke (57.8%). Logistic regression analysis identified diabetes (OR=3.70; CI=1.76-7.77) as independent risk factor for ischemic stroke. The ischemic stroke was most common type of stroke. Hypertension and diabetes were important risk factors for stroke.KEY WORDS: stroke, Brazil, hypertension. Freqüência dos tipos de acidente vascular cerebral em hospital de emergência, Natal, BrasilRESUMO -Realizamos um estudo de prevalência para determinar a freqüência dos tipos de acidente vascular cerebral (AVC) num hospital de urgência de Natal. Estudaram-se todos os pacientes que foram admitidos no hospital de urgência com diagnóstico presuntivo de AVC. Dos 416 pacientes, 328 foram estudados, 88 foram excluídos por não cumprirem os critérios de inclusão, 74,7% (n= 245) tiveram AVC isquêmi-co, 17,7% (n=58) hemorragia intracerebral e 7,6% (n=25) hemorragia subaracnóidea. O gênero mais prevalente foi o masculino (52,7%). A média de idade foi 64,1 anos. A letalidade intra-hospitalar foi de 10,2%, 17,2% e 36% para o tipo isquêmico, hemorrágico e hemorragia subaracnóide, respectivamente. O principal fator de risco modificável foi a hipertensão arterial sistêmica (HAS) para AVC isquêmico (67,6%) e AVC hemorrágico (57,8%). A regressão logística identificou diabetes como fator de risco independente para AVC isquêmico (OR=3,70; IC=1,77 Dr. Mario E. Dourado -Rua Marcílio Furtado 2042 -59063-360 Natal RN -Brasil. E-mail: medourado@digi.com.br Stroke has become an increasingly important health problem worldwide. There are about 5.5 million yearly deaths and an estimated loss of 49 million disability-adjusted life years worldwide 1-4 . Hypertension and age are the main risk factors for the different types of stroke, which include ischemic (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH). The management strategies of these ailments are distinct, since they are heterogenous diseases 5 . There has been a decreasing trend in incidence and mortality from stroke in the USA and Europe 6,7 . In contrast, its incidence has increased in developing countries, which may be due to the rapid aging of the population, and increased prevalence of stroke risk factors resulting from change in diet, sedentary lifestyle and diabetes 2 . Lavados et al. showed a raw annual stroke incidence of 95.8 p...

show abstract

Section: Discussionmentioning

confidence: 99%

Frequency of stroke types at an emergency hospital in Natal, Brazil

Martins

Figueiredo

Rocha

et al. 2007

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

show abstract

“…Individuals of Asian, African, and Latin American origin tend to have a higher frequency of primary hemorrhage than persons of European origin [1]. In addition, although primary hemorrhage accounts for 10 to 17% of all strokes in Western countries, in Asian it is approximately 25% [3].…”

Section: Prevalence and Incidencementioning

confidence: 99%

“…Some of the potentially modifiable ischemic stroke risk factors being studied are listed in Table 2 [21,22]. Risk factors for primary intracerebral hemorrhage are shown in Table 3 and overlap to some degree with those for ischemic stroke [3].…”

Section: Risk Factorsmentioning

confidence: 99%

Stroke Epidemiology: Advancing Our Understanding of Disease Mechanism and Therapy

2011

View full text Add to dashboard Cite

Stroke is the fourth killer and number one cause of adult disability in the United States. The estimated direct and indirect costs of stroke care in this country are $68.9 billion for 2009. The prevalence of stroke and its cost will undoubtedly rise as the aging population increases. In addition, stroke incidence and mortality are increasing in less developed countries in which the lifestyles and population restructuring are rapidly changing. More population-based research to assess incidence, risk factors, and outcomes are needed in these countries. Epidemiologic studies can help identify groups of individuals or regions at higher risk for stroke. They can also help us better understand the natural history of certain conditions and therefore push the direction of therapeutic investigations. Furthermore, the study of trends across different time periods and different populations can help investigators evaluate the effects of stroke care programs and treatment options.

show abstract

“…The strongest risk factor for cerebral hemorrhage is widely recognized to be hypertension 9, 10, 11, 12, 13. In the Secondary Prevention of Small Subcortical Strokes (SPS3) trial, the rate of hemorrhagic stroke was significantly reduced by a systolic blood pressure target of <130 mm Hg, compared with a systolic blood pressure target of 130 to 149 mm Hg in patients receiving aspirin alone or aspirin plus clopidogrel 14.…”

Section: Discussionmentioning

confidence: 99%

Aspirin for primary stroke prevention in elderly patients with vascular risk factors

Uchiyama

2017

J of Gen and Family Med

View full text Add to dashboard Cite

The effect of aspirin in primary stroke prevention is controversial in Western population, and no evidence is available in Asian population. We performed stroke subanalysis of the Japanese Primary Prevention Project (JPPP), which was a randomized controlled trial of aspirin vs no aspirin for primary prevention of vascular events in 14 464 patients aged over 60 years with hypertension, diabetes, and/or dyslipidemia. We evaluated the effects of aspirin on the risk of stroke and intracranial hemorrhage. Aspirin did not show any net benefit for primary stroke prevention during median follow‐up for 5 years, because nonsignificant reduction in ischemic stroke was offset by nonsignificant increase in hemorrhagic stroke. Aspirin is not recommended for primary stroke prevention in elderly Japanese patients with vascular risk factors in general. Asymptomatic large artery atherosclerosis appears to be a new target for primary prevention of stroke.

show abstract

Risk Factors for Intracerebral Hemorrhage in the General Population

Cited by 674 publications

References 37 publications

Frequency of stroke types at an emergency hospital in Natal, Brazil

Frequency of stroke types at an emergency hospital in Natal, Brazil

Stroke Epidemiology: Advancing Our Understanding of Disease Mechanism and Therapy

Aspirin for primary stroke prevention in elderly patients with vascular risk factors

Contact Info

Product

Resources

About