“…However, UUT-UC correlates with a high incidence of tumor recurrence and a poor patient outcome. Although the pathological findings, including the tumor size, tumor number, tumor grade, stage, lymph node involvement, and lymphovascular invasion, are thought to be predictors of recurrence [2][3][4][5], a new marker that more precisely predicts the prognosis prior to nephroureterectomy is needed to help provide additional treatment, such as neoadjuvant systemic chemotherapy.…”