1992
DOI: 10.1093/oxfordjournals.aje.a116488
|View full text |Cite
|
Sign up to set email alerts
|

Risk Factors for Invasive Haemophilus influenzae Type b in Los Angeles County Children 18-60 Months of Age

Abstract: Potential factors that confer risk or protection for invasive Haemophilus influenzae type b disease were evaluated in Los Angeles County children 18-60 months of age by case-control methods. In this age group, 79 H. influenzae type b cases were identified by overlapping surveillance methods, and 221 random controls were selected by random digit dialing. Cases and controls were similar in sex, prior health, proportion attending day care, parental educational level, history of breast feeding, and proportion vacc… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

0
20
0

Year Published

1994
1994
2018
2018

Publication Types

Select...
6
2

Relationship

0
8

Authors

Journals

citations
Cited by 31 publications
(20 citation statements)
references
References 0 publications
0
20
0
Order By: Relevance
“…18 A dose-response effect has also been reported for this risk depending on the number of hours spent in the day nursery, 11 -13 and is higher in the first month of schooling. 14 However, many studies, including ours, do not find this relationship, 17,24 and even find the opposite, that this has a protective effect. 19 In day nurseries, children are exposed to early contact with diverse of microbial flora, and inflammation of the respiratory mucosa is frequent; therefore, there is an increased possibility of contact with Hib, followed by invasive disease.…”
Section: Discussionmentioning
confidence: 66%
“…18 A dose-response effect has also been reported for this risk depending on the number of hours spent in the day nursery, 11 -13 and is higher in the first month of schooling. 14 However, many studies, including ours, do not find this relationship, 17,24 and even find the opposite, that this has a protective effect. 19 In day nurseries, children are exposed to early contact with diverse of microbial flora, and inflammation of the respiratory mucosa is frequent; therefore, there is an increased possibility of contact with Hib, followed by invasive disease.…”
Section: Discussionmentioning
confidence: 66%
“…These findings illustrate an increase in prevalence (1.3%) from that previously reported among pre-school aged children during years 1995-6 in the UK. 56 Children fully vaccinated against Hib, with anticapsular antibody concentrations Overcrowding has similarly been associated with an increased risk of invasive Hib in Los Angeles County, 74 Oklahoma, US 73 and Alaskan natives. 19 Furthermore, over three study sites in Alaska persistent Hib carriage was noted in those with limited access to running water, flush toilets, as well as household crowding and poor house ventilation.…”
Section: Risks Associated With Hib Carriagementioning
confidence: 99%
“…25 This is comparable with findings in the US, which also identified smoking as a risk factor for invasive Hib disease. 73,74 However, Lee et al failed to find a significant increase in invasive Hib disease with passive smoking. 75 Lastly, defects in immunity have been associated with increases in susceptibility for invasive Hib disease.…”
Section: Risks Associated With Hib Carriagementioning
confidence: 99%
“…These include the use of shared child care facilities, 3-7 large family size or crowding, 5,6,8,9 low socioeconomic status, 8 and smoking. 8 Breast feeding has been shown to be protective. 3,5,6,9,10 In a case-control study of Navajo children, we investigated these and other factors that were unique to the environmental and cultural characteristics of this population, including heating fuels, husbandry practices, and arts and crafts activities.…”
mentioning
confidence: 99%
“…These include the use of shared child care facilities, [3][4][5][6][7] large family size or crowding, 5,6,8,9 low socioeconomic status, 8 and smoking. 8 Breast feeding has been shown to be protective.…”
mentioning
confidence: 99%