Risk Factors for Mortality and Postoperative Complications After Gastrointestinal Surgery

Abstract

Premorbid factors, characteristics of the disease, the patients' preoperative condition, operative factors, and the surgeon's training are all associated with surgical outcome across different gastrointestinal operations and should be assessed when auditing surgical outcome.

Retrospective Analysis of Preperitoneal MeshRepair in Incisional Hernia-A 3years Study

“…Collagen constitutes approximately one -third of the total protein content of any organism and is the predominant structural protein of the aponeurosis, where it is organized in fibres, whose chemical-physical characteristics render them particularly resistant to traction. Within the abdominal wall, as in other tissue, damaged collagen fibers are repaired through a process of proliferation and remodelling [7]. The aim of MMP proteolytic activity is to permit the passage of macrophages and fibroblasts across hydrolysed collagen fibres, leading to tissue repair where necessary.…”

Post‐operative serious adverse events in a mixed surgical population – a retrospective register study

“…Several studies have investigated the mortality and post-operative complications in a wide variety of surgical populations, [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] but in the majority of studies, observation time is short and appears to vary between in-hospital, 30-day, and 90-day mortality.…”

Surgery-related risk factors

“…Several studies [25][26][27] confirmed that certain complex interventions carry the risk of increased complication rates when carried out by a nonspecialized surgeon or, similarly important, in a nonspecialized institution. In some studies [28,29], elective patients operated on by nonspecialized surgeons had almost twice the risk of postoperative death in gastrointestinal surgery. On the contrary, higher hospital caseload is not significantly associated with better outcomes in emergency colectomy [30].…”

“…Within almost every surgical specialty, it has been shown that training is associated with outcome [28] to some extent. The training of surgical residents is permanently changing with new techniques and political issues relevant to working hour restrictions.…”