Risk factors for postoperative complications in lensectomy–vitrectomy with or without intraocular lens placement in ectopia lentis associated with Marfan syndrome

Fan, Fan; Luo, Yi; Liu, Xin; Lu, Yi; Zheng, Tianyu

doi:10.1136/bjophthalmol-2013-304144

Cited by 37 publications

(49 citation statements)

References 28 publications

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“…Moreover, the risk is higher in surgically treated patients, especially after eye trauma (Fan et al. ). In our series, the presence of the IOL did not impede vitreous surgery, which was completed with good visualization even with the IOL in place.…”

Section: Discussionmentioning

confidence: 99%

Anterior iris‐claw intraocular lens implantation for the management of nontraumatic ectopia lentis: long‐term outcomes in a paediatric cohort

Català‐Mora

Cuadras

Díaz-Cascajosa

et al. 2016

Acta Ophthalmologica

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Section: Discussionmentioning

confidence: 99%

Anterior iris‐claw intraocular lens implantation for the management of nontraumatic ectopia lentis: long‐term outcomes in a paediatric cohort

Català‐Mora

Cuadras

Díaz-Cascajosa

et al. 2016

Acta Ophthalmologica

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“…Well-described complications of pars plana lensectomy in MFS include retinal detachment, vitreous hemorrhage, lens implant decentration, and glaucoma. [ 7 ] One similar case was noted in the literature, where Mancino et al . described a 34-year-old woman in Italy with MFS, who developed chronic hypotony 20 years after 20-gauge pars plana lensectomy.…”

Section: Discussionmentioning

confidence: 57%

Delayed sclerotomy wound dehiscence after lensectomy and vitrectomy in Marfan syndrome

Sridhar¹,

Chang²,

Aziz³

et al. 2015

Oman J Ophthalmol

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Marfan syndrome (MFS) is associated with abnormal fibrillin development that can cause morbidity and mortality. A case of acute onset hypotony due to sclerotomy wound dehiscence 13 years after 20-gauge pars plana vitrectomy and lensectomy is reported in a patient with MFS. Slit lamp examination revealed a leaking sclerotomy wound and intraoperatively the source was noted to be the prior sclerotomy site. On postoperative follow-up, the patient's vision returned to baseline, and intraocular pressure normalized. Twenty-gauge sclerotomy wound dehiscence may occur years after surgery, especially in patients with abnormal collagen as in MFS.

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“…About 30% of eyes had relatively long AL (Z-AL score ≥ 3), and the largest had a Z-score of 10.68. A long AL has been proven to be a risk factor for retinal detachment 26 and open-angle glaucoma 27 in the eyes of MFS patients.…”

Section: Discussionmentioning

confidence: 99%

Analysis of axial Length of Marfan Syndrome with Bilateral Ectopia Lentis by Z-scores for Chinese Patients under 20 years Old

Chen¹,

Chen²,

Zhang³

et al. 2020

Preprint

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Purpose: To analyze the axial length (AL) in young patients with Marfan syndrome (MFS) and bilateral ectopia lentis (EL) before the lens surgery. Methods: This study reviewed MFS patients under 20 with bilateral EL from January 2015 to October 2020. The Z-scores were introduced in terms of the number of standard deviations (SD) from the mean of age-matched normative data. Using Z-scores, the distribution of AL and influence factors were evaluated. The correlations between AL and other biometrics were analyzed. Results: We reviewed 183 patients, and enrolled both eyes. The mean age was 8.44 ± 4.69 years old. The mean AL increased from 23.41 ± 1.73 mm under 5 years old to 26.40 ± 2.28 mm in the 16-20 age group, and when plotted, the trend presented a logarithmic curvature. The mean Z-AL score was 1.74 ± 2.68. One-third of eyes had Z-score < 0. The right eye and the eye complicated with megalocornea had larger Z-AL scores. A positive correlation was found between Z-AL and Z-Corneal Curvature Radius (r = 0.265, P < 0.001).Conclusion: Young patents with bilateral EL but small AL should not be excluded from MFS without systematic examination. The age-adjusted Z-score will facilitate further study of the individual variations in AL across different ages.

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Risk factors for postoperative complications in lensectomy–vitrectomy with or without intraocular lens placement in ectopia lentis associated with Marfan syndrome

Abstract: Development of RD in patients with Marfan syndrome remains a risk following surgery for ectopia lentis. Caution should be taken in eyes with severe lens dislocation or high axial myopia when planning the surgery.

Cited by 37 publications

References 28 publications

Anterior iris‐claw intraocular lens implantation for the management of nontraumatic ectopia lentis: long‐term outcomes in a paediatric cohort

Anterior iris‐claw intraocular lens implantation for the management of nontraumatic ectopia lentis: long‐term outcomes in a paediatric cohort

Delayed sclerotomy wound dehiscence after lensectomy and vitrectomy in Marfan syndrome

Analysis of axial Length of Marfan Syndrome with Bilateral Ectopia Lentis by Z-scores for Chinese Patients under 20 years Old

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