Risk factors for prolonged hospitalization and delayed treatment completion after laparoscopic appendectomy in patients with uncomplicated acute appendicitis

Shin, Ji‐Young; Ihn, Myong Hoon; Kim, Kyung Sik; Kim, Sang Hyun; Lee, Jihyoun; Yun, Sangchul; Cho, Sung Woo

doi:10.3393/ac.2021.00773.0110

Cited by 4 publications

(1 citation statement)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This cross-sectional study was performed at Khyber Teaching Hospital, Peshawar, from Feburary to August 2018. Sample Size: The sample size was 216 taking a sensitivity of CRP of 85.1%, specificity of CRP of 72% 17 , and prevalence of acute appendicitis of 22.71% 18 while a confidence interval of 95% and 10% margin of error. Sampling Technique: Non-probability consecutive sampling.…”

Section: Methodology Study Design Setting and Durationmentioning

confidence: 99%

Socioeconomic, Laboratory and Associated Factors in Patients Suffering From Acute Appendicitis

Tahir¹,

Ali²,

Usman³

et al. 2023

PJMHS

View full text Add to dashboard Cite

Background: Acute appendicitis (AA) is the most common clinical condition worldwide. In Pakistan, about 400,000 appendectomies are routinely carried out in surgical departments yearly. This study aims to find the latest and updated information regarding the diagnostic accuracy of CRP levels in AA. This will help surgeons make timely decisions, thus reducing the morbidity and mortality associated with complicated appendicitis. Methods: This descriptive cross-sectional study was performed at KTH Peshawar from February to august 2018. It was designed to analyze C-reactive protein levels among acute appendicitis patients using positive and negative predictive values. Histopathologically confirmed appendicitis patients were included. Results: In the current study, 216 patients suffering from Acute appendicitis were studied observed. The symptoms duration was < 2days in 75% patients while >2 days symptoms were found in 25% population. Majority patients were poor (46%), followed by middle class (42%), and rich (12%). Obesity was only observed in 22% patients suffering from AA. Diabetes and hypertension was observed in 18% and 15% patients respectively. Diagnostic accuracy of acute appendicitis was also calculated between CRP and Histopathology findings based on age, diabetes mellitus, gender, hypertension, obesity, and period of symptoms. Conclusion: Our study concludes that the acute appendicitis symptoms appeared in less than two days. Acute appendicitis predominantly found in poor and middle class patients. Acute appendicitis should be diagnosed based mostly on its clinical symptoms. Despite the fact that CRP is a particularly helpful marker in the clinical diagnosis of acute appendicitis, general surgeons must apply their clinical judgement. The function of CRP in acute appendicitis should be examined in future research with a bigger sample size. Keywords: C-reactive protein level, Socioeconomical factors, Acute Appendicitis, Diagnostic accuracy, Histopathological.

show abstract

Section: Methodology Study Design Setting and Durationmentioning

confidence: 99%

Socioeconomic, Laboratory and Associated Factors in Patients Suffering From Acute Appendicitis

Tahir¹,

Ali²,

Usman³

et al. 2023

PJMHS

View full text Add to dashboard Cite

show abstract

Nomogram prediction model for length of hospital stay following laparoscopic appendectomy in pediatric patients: a retrospective study

Liu,

Yang,

Gou

et al. 2024

Front. Pediatr.

View full text Add to dashboard Cite

ObjectiveThe aim of this research was to develop and internally validate a nomogram for forecasting the length of hospital stay following laparoscopic appendectomy in pediatric patients diagnosed with appendicitis.MethodsWe developed a prediction model based on a training dataset of 415 pediatric patients with appendicitis, and hospitalization data were collected retrospectively from January 2021 and December 2022. The primary outcome measure in this study was hospital length of stay (LOS), with prolonged LOS defined as admission for a duration equal to or exceeding the 75th percentile of LOS, including the discharge day. Risk factor analysis was conducted through univariate and multivariate logistic regression analyses. Based on the regression coefficients, a nomogram prediction model was developed. The discriminative performance of the predicting model was evaluated using the C-index, and an adjusted C-index was computed through bootstrapping validation. Calibration curves were generated to assess the accuracy of the nomogram. Decision curve analysis was conducted to determine the clinical utility of the predicting model.ResultsPredictors contained in the prediction nomogram included Age, neutrophil-to-lymphocyte ratio, C-reactive protein level, operative time, appendiceal fecalith, and drainage tube. The C-index of the prediction nomogram was determined to be 0.873 (95% CI: 0.838–0.908), with a corrected C-index of 0.8625 obtained through bootstrapping validation (1,000 resamples), indicating the model's favorable discrimination. Calibration curves illustrated a strong agreement between predicted and observed outcomes. According to the decision curve analysis of the nomogram, the predictive model demonstrates a net benefit at threshold probabilities exceeding 2%.ConclusionThis nomogram, incorporating variables such as Age, neutrophil-to-lymphocyte ratio, C-reactive protein level, operative time, appendiceal fecalith, and drainage tube, offers a convenient method for assessing the duration of hospitalization in pediatric patients with appendicitis.

show abstract

Non-linear association between C-reactive protein levels and length of stay in pediatric appendicitis patients undergoing laparoscopic appendectomy

Liu,

Yang,

Gou

2024

Front. Pediatr.

View full text Add to dashboard Cite

ObjectiveTo examine the correlation between C-reactive protein (CRP) levels at hospital admission and the length of stay (LOS) in pediatric patients with appendicitis who underwent laparoscopic appendectomy.MethodsWe retrospectively collected the clinical data from pediatric patients diagnosed with acute appendicitis and treated with laparoscopic appendectomy. Multivariate generalized linear regression analyses were performed to determine the independent relationship between CRP and LOS. Smooth curve fitting was constructed to examine the potential non-linear relationship between CRP and LOS. A segmented regression model was used to calculate threshold effects and determine the inflection point.ResultsA total of 815 participants were included in the study. Multiple linear regression analysis indicated that the higher the CRP levels, the longer the LOS. Fully adjusted smooth curve fitting suggested a non-linear relationship between CRP and LOS. A segmented regression showed that the inflection point value of CRP was 34.13 mg/L. A 1 mg/L increase in CRP levels was significantly associated with a 0.013-day increase in length of stay (95% CI: 0.009, 0.018; P < 0.001) when CRP levels > 34.13 mg/L. However, there was no significant association between CRP and LOS when CRP levels < 34.13 mg/L (P > 0.05).ConclusionThere was a non-linear association and threshold effect between CRP levels and LOS. CRP levels above 34.13 mg/L were associated with longer LOS in pediatric appendicitis patients. These findings contribute to the understanding of inflammatory markers in recovery dynamics and underscore the necessity for further research to investigate their potential clinical implications.

show abstract

Risk factors for prolonged hospitalization and delayed treatment completion after laparoscopic appendectomy in patients with uncomplicated acute appendicitis

Cited by 4 publications

References 26 publications

Socioeconomic, Laboratory and Associated Factors in Patients Suffering From Acute Appendicitis

Socioeconomic, Laboratory and Associated Factors in Patients Suffering From Acute Appendicitis

Nomogram prediction model for length of hospital stay following laparoscopic appendectomy in pediatric patients: a retrospective study

Non-linear association between C-reactive protein levels and length of stay in pediatric appendicitis patients undergoing laparoscopic appendectomy

Contact Info

Product

Resources

About