“…5 Ketamine administered by intravenous or intramuscular routes, even as a single drug, has been indicated as a safe and effective alternative for rapid analgesia. 6,10,27,28 In a systematic review of randomized trials of analgesia and sedation for reduction of fractures in children at a PEU, ketamine/ midazolam proved to be more effective as an analgesic and had fewer adverse effects than combinations of fentanyl/midazolam or propofol/midazolam. 1,2,4,5,15,25 When the level of satisfaction of parents and orthopedists were analyzed with analgesia for the orthopedic procedure, it was found that levels were quite high.…”