2023
DOI: 10.1007/s00431-023-04988-0
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Risk factors for the development of tuberculosis among the pediatric population: a systematic review and meta-analysis

Abstract: Pediatric tuberculosis is a major cause of mortality and morbidity in children due to high transmission, poor diagnostic tools, and various respiratory diseases mimicking TB. Identifying risk factors will provide evidence for clinicians to strongly relate their diagnosis to the associated pathology. Studies were retrieved from PubMed, Embase, and Google Scholar, systematically reviewed, and meta-analyzed for various risk factors and their association with pediatric TB. Meta-analysis depicted that four out of e… Show more

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Cited by 9 publications
(2 citation statements)
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“…These five aspects have been identified as risk factors in previous systematic reviews informing the programme [ 6 , 7 , 8 , 9 ]. Moreover, socioeconomic status, sex, and age have been reported as important effect modifiers for the risk of TB disease ( 10 ).…”
Section: Introductionmentioning
confidence: 99%
“…These five aspects have been identified as risk factors in previous systematic reviews informing the programme [ 6 , 7 , 8 , 9 ]. Moreover, socioeconomic status, sex, and age have been reported as important effect modifiers for the risk of TB disease ( 10 ).…”
Section: Introductionmentioning
confidence: 99%
“…Globally in 2022, 16% of the HIV-negative and 18% of HIV-positive people who died from TB were children aged < 15 years [ 1 ]. Available data on children suggests limited access to diagnosis and treatment and a higher risk of developing TB among exposed infants and young children [ 1 , 5 , 6 ]. Worldwide, There is a large gap in case detection among children.…”
Section: Introductionmentioning
confidence: 99%