2016
DOI: 10.1371/journal.pone.0166654
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Risk Factors for the Rupture of Middle Cerebral Artery Bifurcation Aneurysms Using CT Angiography

Abstract: Background and PurposeTo investigate the clinical and morphological characteristics associated with risk factors for the rupture of bifurcation-type middle cerebral artery aneurysms (MCAAs).MethodsA total of 169 consecutive patients with 177 bifurcation-type MCAAs were reviewed from August 2011 to January 2016. Based on the clinical and morphologic characteristics findings, the risk factors of aneurysm rupture were assessed using statistical methods.ResultsAge, cerebral atherosclerosis, no hypertension, hypert… Show more

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Cited by 31 publications
(29 citation statements)
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“…This form of aneurysm was described by Weir in 1987 [28]. In recent years, more and more researchers [4,8,11,16,22,23] point to the fact that ruptured aneurysms have irregular shape. From the mechanical point of view, wall of an aneurysm with inhomogeneities can have an inhomogeneous stress field, and structure of the flow inside such aneurysms becomes unstable and inhomogeneous.…”
Section: Discussionmentioning
confidence: 89%
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“…This form of aneurysm was described by Weir in 1987 [28]. In recent years, more and more researchers [4,8,11,16,22,23] point to the fact that ruptured aneurysms have irregular shape. From the mechanical point of view, wall of an aneurysm with inhomogeneities can have an inhomogeneous stress field, and structure of the flow inside such aneurysms becomes unstable and inhomogeneous.…”
Section: Discussionmentioning
confidence: 89%
“…Mortality with subarachnoid hemorrhage is up to 45%, and half of survivors have serious neurological problems [3]. Taking into account the high mortality rate, the issue of the need for carrying out preventive surgical or endovascular treatment of an unruptured aneurysm in each case remains open, as it can be associated with serious postoperative complications [4]. Therefore, the problem of developing reliable and objective criteria to assess the risk of rupture is relevant.…”
Section: Introductionmentioning
confidence: 99%
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“…Older age is assigned higher risk in the PHASES score [15], and was associated with higher risk of aneurysm growth in a recent study [2]. However, other studies suggested higher risk for younger patients in anterior communicating aneurysms [21], middle cerebral artery aneurysms [32], and in general [18]. …”
Section: Discussionmentioning
confidence: 99%