2019
DOI: 10.1159/000499120
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Risk Factors for Transfusion after Orthotopic Liver Transplantation

Abstract: <b><i>Background:</i></b> Transfusion of blood products during orthotopic liver transplantation (OLT) is associated with increased morbidity and mortality. Although risk factors associated with intraoperative transfusion requirements have been widely assessed, published data on the prediction of postoperative transfusion requirements are sparse. <b><i>Objectives:</i></b> The aim of this study was to evaluate risk factors for postoperative allogeneic transfusion r… Show more

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Cited by 11 publications
(6 citation statements)
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“…Advances in surgical techniques and anaesthetic management have contributed to an overall reduction in the transfusion needs during and following liver transplantation. Despite blood management, liver transplantation is still associated with high blood transfusion requirements perioperatively because of abnormal haemostasis and bleeding complications [2,3]. D-negative patients are routinely transfused with D-negative red blood cells (RBCs) because of the high immunogenicity of the D antigen.…”
Section: Introductionmentioning
confidence: 99%
“…Advances in surgical techniques and anaesthetic management have contributed to an overall reduction in the transfusion needs during and following liver transplantation. Despite blood management, liver transplantation is still associated with high blood transfusion requirements perioperatively because of abnormal haemostasis and bleeding complications [2,3]. D-negative patients are routinely transfused with D-negative red blood cells (RBCs) because of the high immunogenicity of the D antigen.…”
Section: Introductionmentioning
confidence: 99%
“…This is of vital importance as increased transfusion of blood products is highly correlated with liver transplant morbidity and mortality. [ 28 ] Of note, FFP and cryoglobulin were also transfused more on average in the non‐PVR‐TIPS group. These differences may have been significant if our study had a higher sample size of patients to analyze.…”
Section: Discussionmentioning
confidence: 99%
“…High intraoperative blood loss is anticipated during LT owing to coagulopathy, portal hypertension, collateral vessels, and complex surgical procedures including anastomosis of major vessels [1]. Therefore, allogeneic blood transfusion is common, and rates of perioperative allogeneic blood transfusion remain elevated in patients undergoing LT (50.5%-62.6%) [2,3]…”
Section: Introductionmentioning
confidence: 99%