“…A strong relationship between thrombosis and cancer metastasis has been elucidated in the literature. [33][34][35] During metastasis, platelets play an important role in promoting tumor cell growth, invasion, survival in the circulation, extravasation and the overgrowth of these existing cells in distant organs. 8 Here, we demonstrated the use of a liposomal therapy as a straightforward approach to repurpose platelets in situ to effectively target and kill CTCs in the bloodstream while minimizing any cytotoxic effects to normal tissues.…”