Risk Factors, Microbiological Findings, and Clinical Outcomes in Cases of Microbial Keratitis Admitted to a Tertiary Referral Center in Ireland

Saeed, Ahmed; Darcy, Fiona; Stack, Jim; Collum, Louis M; Power, William; Beatty, Stephen

doi:10.1097/ico.0b013e3181877a52

Cited by 84 publications

(52 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Contact lens wear, trauma, and ocular surface disease [1,2,[6][7][8] are factors increasing the risk for the development of this condition. The treatment customarily consists of topically administered antibiotics.…”

Section: Introductionmentioning

confidence: 99%

UVA-riboflavin photochemical therapy of bacterial keratitis: a pilot study

Makdoumi

Mortensen

Sorkhabi

et al. 2011

Graefes Arch Clin Exp Ophthalmol

161

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

UVA-riboflavin photochemical therapy of bacterial keratitis: a pilot study

Makdoumi

Mortensen

Sorkhabi

et al. 2011

Graefes Arch Clin Exp Ophthalmol

161

View full text Add to dashboard Cite

show abstract

“…Presentation in this age was more common due to the fact that persons belonging to this age group are more active and involve themselves in outdoor activities. Another factor could be that they are also the earning member of the family so are brought more frequently to the hospital (Saeed A et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

Direct microscopy in suppurative keratitis: a report from tertiary level hospital in Nepal

Gautam

Chaudhary²,

Sharma³

et al. 2017

Nep J Oph

View full text Add to dashboard Cite

Introduction: Infective keratitis is an ocular emergency that requires prompt diagnosis for appropriate management. This study was done todetermine the sensitivity, specificity and predictive values of Gram stain and potassium hydroxide (KOH) wet mount in the diagnosis of suppurative keratitis. Materials and methods: A prospective hospital based study of all patients with clinically diagnosed suppurative keratitis presenting between January 2011 and June 2012 was carried out. Corneal scrapes were taken and subjected to direct microscopy and culture.Results: Corneal scrapings were obtained from 108 eyes with suppurative keratitis. Direct microscopy was positive in 39.2% of cases and organisms were grown in 50.9 % of the cases. Bacteria were responsible in 76.4% and fungi in 23.6%. Of the bacterial isolates, 66.7% was Staphylococcus aureus and of the fungal isolates, 30.7% was Aspergillus species. Sensitivity in vitro showed that Cefazolin, Chloramphenicol and Ofloxacin were most effective against bacteria. Sensitivity of Gram stain in detecting bacteria was 50% (95% CI, 34.43 to 65.56) and specificity was 77.3% (95% CI, 65.0 to86.3) and sensitivity of KOH wet mount in detecting fungi was 53.8% (95% CI, 26.12 to79.6) and specificity was 98.9% (95% CI, 93.44 to 99.9). Positivity of direct smear (65.1%) was found to be higher among eyes with larger ulcers (>2mm) than eyes with smaller ulcers (<2mm). Conclusion: Direct microscopy is of great diagnostic value in the management of suppurative keratitis and it is recommended in all ophthalmic clinics without exception for establishing timely, appropriate and effective treatment.

show abstract

“…The incidence of ulcerative keratitis in human immunodeficiency virus-positive patients was 238.1 per 100 000 personyears. (18) Etiology: -The regular danger variables for corneal keratitis incorporate visual injury, contact lens wear, recent visual surgery, previous visual surface disease, dry eyes, lid deformity, corneal sensation impairment, chronic use of topical steroids and systemic immunosuppression (32,33,24) .…”

Section: Epidemiology Of Corneal Ulceration: -mentioning

confidence: 99%