Risk factors of avascular necrosis in Takayasu arteritis: a cross sectional study

Gökçen, Neslihan; Komaç, Andaç; Tuncer, Fatma Betül; Buyuksutcu, Gizem Kocak; Işık, Ö. Özdemir; Yazıcı, Ayten; Çefle, Ayşe

doi:10.1007/s00296-021-04909-0

Cited by 2 publications

(4 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After a full-text review, 31 studies were excluded due to insufficient data, 1 due to poor quality (low NOS score) and 1 due to an overlapping cohort ( Figure 2 ). Overall, 6 studies were included [ 31 , 32 , 33 , 34 , 35 , 36 ].…”

Section: Resultsmentioning

confidence: 99%

“…Similarly, in the study by Lim et al, among 144 patients with primary brain tumors who received corticosteroids, the risk of AVN was increased significantly, but there were only 9 patients with diabetes [ 36 ]. The risk of AVN was not related to diabetes in the study by Gokcen et al among 29 patients with Takayasu arteritis, but all of the patients in that study used corticosteroids [ 32 ].…”

Section: Discussionmentioning

confidence: 99%

“… Forest plot showing the association between diabetes and risk of osteonecrosis in sites other than the jaw (odds ratios > 1 indicate increased risk of AVN in sites other than the jaw among patients with diabetes) [ 31 , 32 , 33 , 34 , 35 , 36 ]. …”

Section: Figurementioning

confidence: 99%

See 2 more Smart Citations

Does Diabetes Mellitus Increase the Risk of Avascular Osteonecrosis? A Systematic Review and Meta-Analysis

Konarski

Poboży

Kotela

et al. 2022

IJERPH

View full text Add to dashboard Cite

Avascular osteonecrosis (AVN) is caused by the disrupted blood supply to the bone. Most AVN cases occur in the femoral head, but other sites might be affected as well, including the jaw or distal bones of the extremities. Previous studies suggested that diabetes could increase the risk of AVN of the jaw, but the relationship between diabetes and AVN in other bone sites is unclear. This systematic review and meta-analysis aimed to summarize the evidence from studies that had reported on the occurrence of AVN in sites other than the jaw, depending on the diagnosis of diabetes. Overall, we included 6 observational studies carried out in different populations: primary or secondary AVN of the femoral head, Takayasu arteritis, general population, kidney transplant recipients, systemic lupus erythematosus, and primary brain tumors. A random-effects meta-analysis showed that the risk of AVN in sites other than the jaw was non-significantly increased in patients with diabetes (odds ratio: 1.90, 95% confidence interval: 0.93–3.91). The pooled estimate increased and was significant after the exclusion of one study (2.46, 1.14–5.32). There was a significant heterogeneity (I2 = 65%, tau2 = 0.48, p = 0.01; prediction interval, 0.21–16.84). There was no significant publication bias (p = 0.432). In conclusion, diabetes could increase the risk of AVN in sites other than the jaw, but the available evidence is limited. There is a need for large, well-designed, population-based studies.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Does Diabetes Mellitus Increase the Risk of Avascular Osteonecrosis? A Systematic Review and Meta-Analysis

Konarski

Poboży

Kotela

et al. 2022

IJERPH

View full text Add to dashboard Cite

show abstract

“…The autopsy showed that inflammation caused a significant thickening of the aortic and coronary artery walls and abundant granulomatous and a lymphoplasmacytic infiltrate in the vessel wall [ 26 ]. The avascular necrosis of the vascular wall may also occur [ 27 ]. （2）LM is the most common in coronary artery involvement.…”

Section: Discussionmentioning

confidence: 99%

Clinical and vascular lesion characteristics of the patients with takayasu arteritis manifested firstly as acute myocardial infarction at onset

Liu

Xu²,

Zhou³

et al. 2023

Heliyon

View full text Add to dashboard Cite

Risk factors of avascular necrosis in Takayasu arteritis: a cross sectional study

Cited by 2 publications

References 19 publications

Does Diabetes Mellitus Increase the Risk of Avascular Osteonecrosis? A Systematic Review and Meta-Analysis

Does Diabetes Mellitus Increase the Risk of Avascular Osteonecrosis? A Systematic Review and Meta-Analysis

Clinical and vascular lesion characteristics of the patients with takayasu arteritis manifested firstly as acute myocardial infarction at onset

Contact Info

Product

Resources

About