Risk Factors of Caregiver Burden Evolution, for Patients With Subjective Cognitive Decline or Neurocognitive Disorders: A Longitudinal Analysis

Abstract

ClinicalTrials.govNCT02825732.

Bidirectional relationship between caregiver burden and neuropsychiatric symptoms in patients with Alzheimer's disease: A narrative review

“…A recent longitudinal study demonstrated that coexisting decrease and increase in cognitive function and functional impairment, respectively, and the presence of NPs over time in patients with cognitive decline were independently associated with increased caregiver burden . Another study reported that caregiver burden slightly increased during the 3 years of follow‐up and that NPs and functional impairment of patients with probable AD linked to caregiver burden .…”

“…A recent longitudinal study demonstrated that coexisting decrease and increase in cognitive function and functional impairment, respectively, and the presence of NPs over time in patients with cognitive decline were independently associated with increased caregiver burden. 38 Another study reported that caregiver burden slightly increased during the 3 years of follow-up and that NPs and functional impairment of patients with probable AD linked to caregiver burden. 39 A study by Aguëra-Ortiz et al found that caregiver burden for caregivers of patients with moderate-to-severe AD was reduced during follow-up, due to the fact that NPs, the most important factor related to caregiver burden compared with functional or cognitive decline, decreased in late stage.…”

Factors associated with long-term impact on informal caregivers during Alzheimer’s disease dementia progression: 36-month results from GERAS

“…We found no evidence that a decline in cognition over 18 months, having accounted for all other variables in the models, including the decline in function, was associated with changes in subjective or objective measures of caregiver burden over 36 months. A recent report that a decline in cognitive function (together with increasing functional impairment and level of neuropsychiatric symptoms) was associated with higher caregiver burden in a longitudinal study in patients with subjective cognitive decline or progressive neurocognitive disorder followed for approximately 12 months suggests that reductions in patient cognition may have more of an impact on caregiver burden in the predementia phase (Dauphinot et al, 2016).…”

Prevalence and Risk Factors of Burden Among Caregivers of Older Patients in the Emergency Department The Caregiver Burden of Acutely Presenting Older Patients

“…(27) This study con rms previous research that found a univariate association between caregiver burden and cognitive impairment, ADL dependency, and IADL dependency of patients. (5,25,28,29) After adjusting for the other variables, we found that only cognitive impairment and IADL dependency were associated with a high caregiver burden. This could be explained by the ADL support provided by homecare professionals.…”