Risk factors of childhood tuberculosis: a case control study from rural Bangladesh

Karim, Md Rizwanul; Rahman, M A; Mamun, Shaikh Aa; Alam, Mohamed A; Akhter, Shahnaz

doi:10.4103/2224-3151.206917

Cited by 20 publications

(21 citation statements)

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“…In contrast to this, Gupta R et al, found in his study on children, indicating the high prevalence of childhood tuberculosis in the younger age group. 7,8 Similar findings were reported in hospital-based study done by Sharma S et al, on extra-pulmonary TB during January 1995 -July 2004 at LRS Institute of Tuberculosis and Respiratory Diseases, New Delhi. Patient's where, majority were females (61%) and males were 39%.…”

Section: Discussionsupporting

confidence: 79%

“…Karim MR et al, showed association of maternal education with prevalence of TB cases was statistically significant (p=0.002) in their study. 7 Similarly, Joshi S et al, showed that fathers of 24.24% paediatric patients were illiterate, 13.93% were from middle school, 13.33% from primary school, 32.12% high school. 12 10.30% were intermediate, 4.24% were graduate and the fathers with highest level of education i.e.…”

Section: Discussionmentioning

confidence: 94%

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Assessment of socio-clinical profile of paediatric TB cases admitted to tertiary health care centre, Odisha, India

Jena¹,

Jena²,

Mahapatra³

et al. 2019

Int J Res Med Sci

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Background: Tuberculosis is continued to be a major killer of mankind. Childhood tuberculosis contributes to high mortality due to diagnostic difficulty. Different social factors are responsible for its causation. The objective of the study was to assess the socio clinical factors prevalent among paediatric TB cases admitted to MKCG Medical College.Methods: It was a cross sectional study carried out in the indoor paediatric ward of MKCG medical college. Duration of the study was from August 2016 to July 2017. Study participants were all admitted paediatric cases of age group less than 14 years. Data collected through scientifically designed pretested questionnaires.Results: Total 103 patients were admitted during study period of whom, 54% were male. Their median age was 8 years. They were mostly Hindu by religion (98%) and from lower socioeconomic classes (77%). Majority (60%) were from nuclear family (59%) and families of BPL card holder. Most of their parents had low educational status. Physical overcrowding, inadequate ventilation in the house and smoking were main epidemiological factors observed.Conclusions: It was concluded from the above study group, socioeconomic and environmental risk factors were widely prevalent among them. So, control of these factors are the priority issues to be addressed and improvement of these conditions are recommended for effectiveness of the curative measures.

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Section: Discussionsupporting

confidence: 79%

Section: Discussionmentioning

confidence: 94%

Assessment of socio-clinical profile of paediatric TB cases admitted to tertiary health care centre, Odisha, India

Jena¹,

Jena²,

Mahapatra³

et al. 2019

Int J Res Med Sci

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“…4 7 Anak dengan hunian yang padat berisiko lima kali terinfeksi TB. 8 Infeksi TB sering terjadi pada masa kanak-kanak dan anak dengan infeksi TB berisiko tinggi sakit TB, yang paling rentan anak usia <5 tahun. 3 Dalam penelitian ini didapatkan anak usia <5 tahun memiliki persentase yang lebih tinggi dibandingkan usia >5 tahun, meskipun perbedaan antara kasus dan kontrol tidak bermakna.…”

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Faktor Risiko Sakit Tuberkulosis pada Anak yang Terinfeksi Mycobacterium Tuberculosis

Yustikarini

Sidhartani

2016

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Latar belakang. Tuberkulosis (TB) masih merupakan masalah kesehatan dan penyebab utama mortalitas dan morbiditas pada anak.Anak yang terpapar Mycobacterium Tuberculosis mempunyai risiko tinggi menjadi sakit TB. Terdapat beberapa faktor risiko yangberpengaruh terhadap sakit TB pada anakTujuan. Mengetahui faktor risiko yang berpengaruh terhadap sakit TB anakMetode. Rancangan penelitian kasus kontrol, subjek penelitian terdiri atas 40 anak sakit TB sebagai kelompok kasus dan 40 anakinfeksi TB sebagai kelompok kontrol. Diagnosis ditegakkan dengan menggunakan sistem skoring TB. Faktor risiko yang ditelitimeliputi riwayat kontak, usia, imunisasi BCG, kepadatan hunian, sosial ekonomi, dan pengetahuan. Analisis statistik menggunakanuji chi square untuk analisis bivariat dan regresi logistik untuk analisis multivariat.Hasil. Delapan puluh anak diikutsertakan dalam penelitian, median usia 49,5 bulan (12-156 bulan). Hasil uji statistik menunjukkanbahwa tidak terdapat hubungan bermakna antara usia, imunisasi BCG, status sosial ekonomi dan pengetahuan dengan kejadianTB pada anak. Terdapat hubungan yang bermakna riwayat kontak TB dengan sakit TB OR 18,3 (IK95% 5,12-65,89; p<0,05).Kepadatan hunian dengan kejadian sakit TB OR 6,54 (IK95% 1,05-40,73; p<0,05).Kesimpulan. Riwayat kontak TB dan kepadatan hunian merupakan faktor risiko sakit TB pada anak. Usia muda, imunisasi BCG,status sosial-ekonomi dan pengetahuan tidak terbukti sebagai faktor risiko kejadian sakit TB pada anak yang terinfeksi MycobacteriumTuberculosis

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“…Chest X-rays of the index cases may be used to assess the severity and location of abnormalities in the lungs. 15 Extensive infiltrates and cavities in the upper lobe were risk factors in the transmission of tuberculosis from adults to children. 12 Adverse environmental conditions such as poor ventilation, humid housing conditions, and the number of occupants in the home may also increase tuberculosis incidence.…”

Section: Discussionmentioning

confidence: 99%

Tuberculosis risk factors in children with smear-positive tuberculosis adult as household contact

Hajarsjah

Daulay

Ramayani

et al. 2018

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Background Children in household contact of adults with smear-positive tuberculosis (TB) are at higher risk of TB infection. Screening of these children is a main strategy for eliminating childhood TB.Objective To determine risk factors of TB among children in household contact with smear-positive adult TB patients.Methods This case-control study was conducted in 5 public health centers at Batu Bara District, North Sumatera. We studied children from birth to 18 year-old living in the same house as adults with smear-positive TB. A tuberculosis scoring system was used to diagnosis TB in the children. Associations between risk factors and the incidence of TB were analyzed using Chi-square, Mann-Whitney U, and logistic regression tests.Results We enrolled 145 children who had household contact with smear-positive adult TB patients. Subjects were allocated to either the case group [TB score >6; 61 subjects (42.0%)] or the control group [TB score <6; 84 subjects (58.0%)]. Bivariate analysis revealed that nutritional status, immunization status, number of people in the house, sleeping in the same bed, and duration of household contact had significant associations with the incidence of TB. By multivariate logistic regression analysis, nutritional status and duration of household contact were significant risk factors for TB, with OR 5.89 and 8.91, respectively.Conclusion Malnutrition and duration of household contact with smear-positive adult TB patients of more than 6 hours per day were risk factors for TB among children.

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Risk factors of childhood tuberculosis: a case control study from rural Bangladesh

Abstract: Age, education, father's occupation, crowding, kitchen location and intimate contact with a TB case were significantly associated with smear-positive childhood TB.

Cited by 20 publications

References 1 publication

Assessment of socio-clinical profile of paediatric TB cases admitted to tertiary health care centre, Odisha, India

Assessment of socio-clinical profile of paediatric TB cases admitted to tertiary health care centre, Odisha, India

Faktor Risiko Sakit Tuberkulosis pada Anak yang Terinfeksi Mycobacterium Tuberculosis

Tuberculosis risk factors in children with smear-positive tuberculosis adult as household contact

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