Risk factors of wound infection after lung transplantation: a narrative review

Abstract

Background and Objective: The incidence of incision infection after lung transplantation is prominently high which affect the prognosis. Summarizing the risk factors related to incision infection after lung transplantation contribute to the control of incision infection by pre-controlling the risk factors. The objective is to summarize risk factors related to wound infection after lung transplantation.Methods: PubMed was used to research the literature relating to the risk factors to incision infection after lung transplantation through 1990 to 2022. The retrieval strategy were Medical Subject Heading (MeSH) terms combined entry terms. Two researchers conducted the literature retrieval independently. Two researchers independently evaluate the quality of the literature and summarize the indicators.

Sternal wound infection with Mycoplasma salivarium following bilateral lung transplant

“…1 The incidence of surgical site infection following lung transplantation ranges between 5% and 15%, with surgical wound infections accounting for up to 29% of these cases. 2,3 Gram-positive and gram-negative bacteria are typically the most common pathogens associated with surgical infections in lung transplant cases, accounting for 82% of cases, whereas atypical organisms, including M. hominis, represent only 7%. 3 Positive donor bronchoalveolar lavage fluid cultures are a significant risk factor for surgical wound infection after lung transplantation.…”

“…3 Positive donor bronchoalveolar lavage fluid cultures are a significant risk factor for surgical wound infection after lung transplantation. 2 In one cohort, 23% of surgical site infections were due to pathogens colonizing recipients' native lungs at the time of transplantation. 3 Therefore, surgical seeding from pathogens found in donor or recipient airways is a likely source of these infections.…”