Risk factors related to human papillomavirus infection in oral squamous cell carcinoma

Aim:To estimate the effect of age, period, and birth cohort on mortality from oral and oropharyngeal cancer in Brazil.Methods: Deaths due to oral and oropharyngeal cancer from 1983 to 2017 were analyzed. The effect of age, period, and cohort was calculated using the Poisson regression model. Results:Between 1983 and 2017, 142,634 deaths were recorded from oral and oropharyngeal cancer in Brazil, 54% from oropharyngeal cancer. The male sex contributed to 81% of the deaths. The average mortality rate for men was 4.5 deaths per 100,000 inhabitants, and for women, it was 0.9 deaths per 100,000 inhabitants.There was a strong effect of age on mortality rates from oral and oropharyngeal cancer. The risk increases from 40 years of age in men and 55 years of age in women. An overall period effect was observed. The 2000 period showed the greatest risk when compared to the 1985 period in men. In women, the period of highest risk was 2010.The cohorts born between 1958 and 1962 had a higher risk of death. Conclusions:The period effect is mainly attributed to mortality from oropharyngeal cancer. Most significant values regarding the effect on the cohort groups were observed in female mortality from oral cancer.

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Oral and oropharyngeal cancer mortality in Brazil, 1983–2017: Age–period–cohort analysis

Perea

Antunes

Peres

2020

Oral Diseases

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Influence of sexual habits on human papillomavirus infection risk and oral cancer

Rodríguez-Archilla

Suarez-Machado

2022

Sci Dent J

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Câncer de Trato Digestivo Superior: uma revisão de literatura

Ferreira¹,

Lima²

2023

SHS

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Introdução- O câncer do trato digestivo superior compreende as neoplasias malignas que envolvem estruturas da boca e orofaringe. No Brasil, segundo dados do INCA estima-se 15.190 novos casos da doença para cada ano do triênio 2020-2022, sendo 11.180 em homens e 4.010 em mulheres. Objetivos- Revisar a literatura atual sobre os principais assuntos referente ao câncer do trato digestivo alto. Métodos- Revisão de literatura nas bases de dados PubMed, SciELO,EBSCOhost e Lilacs, de artigos publicadosnos últimos cinco anos, sem restrição de idioma.Foram utilizados para consulta osdescritores: “câncer do trato digestivo”, “neoplasia de boca e orofaringe”, “epidemiologia do câncer de boca e orofaringe”, “prevenção do câncer de boca e orofaringe” e “tratamento do câncer de boca e orofaringe”. Foram descartados artigos que não respeitavam os descritores. Resultados- O tipo histológico mais comum é carcinoma de células escamosas, os principais fatores de riscos são o etilismo e o tabagismo. O diagnóstico na maioria das vezes é realizado tardiamente, comprometendo o bom prognóstico da doença. O tratamento pode ser cirúrgico, radioterápico ou quimioterápico; isoladamente ou em combinação. Conclusões- A literatura atual sobre o câncer do trato digestivo superior consiste em enfatizar a importância do diagnóstico precoce da doença. Possui fatores de risco relacionados ao tabagismo, etilismo, exposição excessiva ao sol, estresse, má alimentação, infecção pelo HPV e má higiene bucal. Mas estudos são necessários para que se avance na imunoterapia, para que os tratamentos sejam menos invasivos e eficientes, proporcionando menos complicações.

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Risk factors related to human papillomavirus infection in oral squamous cell carcinoma

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Oral and oropharyngeal cancer mortality in Brazil, 1983–2017: Age–period–cohort analysis

Oral and oropharyngeal cancer mortality in Brazil, 1983–2017: Age–period–cohort analysis

Influence of sexual habits on human papillomavirus infection risk and oral cancer

Câncer de Trato Digestivo Superior: uma revisão de literatura

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