Risk-focused investigation on ionic liquids against their applied background in transdermal delivery

Curcumin-Based Ionic Liquid Hydrogel for Topical Transdermal Delivery of Curcumin To Improve Its Therapeutic Effect on the Psoriasis Mouse Model

“…Among them, the viscosity of the 1:1 molar ratio was the lowest, and the viscosity increased with the increase in the molar ratio. In addition, thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) showed that the glass transition temperature or melting point of Cur-Car-IL with a 1:1 molar ratio was the lowest, and Cur-Car-IL had good thermal stability. − Therefore, we chose Cur-Car-IL with good stability and a molar ratio of 1:1 as our subsequent experimental study.…”

Enhancing Transdermal Delivery of Curcumin-Based Ionic Liquid Liposomes for Application in Psoriasis

“…Figure S7b showed that the viscosities of all Cur-Bet-IL decrease with increasing temperature. The thermal stability of ILs is very important in drug delivery. − The thermal stability of Cur-Bet-IL was evaluated by using thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC). Cur-Bet-IL begins to decompose at approximately 266 °C ( T dec ), and the glass transition temperature ( T g ) of Cur-Bet-IL with different molar ratios also varies (Figure S7c,d and Table S1).…”

Ultrasound-assisted green and efficient extraction of polysaccharides from Chlorella vulgaris using deep eutectic solvents and improving their performance

“…This shows that Ect-Pan DES can promote the extraction of Chlorella to penetrate the stratum corneum and increase skin permeability. 34,42 In addition, H&E staining revealed that the surface tissue structure of the skin was intact after the skin penetration experiment (Fig. 3f), indicating that Ect-Pan DES did not damage the skin structure.…”

“…The thermal stability of ionic liquids is crucial for drug delivery. [34][35][36] The thermal stability of Ect-Pan DES was evaluated using thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC). Ect-Pan DES decomposes at 136 1C until complete decomposition.…”