Risk for Cardiovascular Disease Early and Late After a Diagnosis of Giant-Cell Arteritis

Bachmeyer, Claude; Buffo, Milene; Soyez, Bérénice

doi:10.7326/l14-5015

Cited by 2 publications

(2 citation statements)

References 4 publications

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“…Incident knee replacement was identified by Read codes 34 (Supplemental Table S1). In addition, we identified incident CVD (i.e., myocardial infarction or stroke) and COPD cases using Read codes 40,41 . Since numerous studies have demonstrated that smoking cessation is associated with a reduced risk of CVD and COPD 25,26 , the findings of smoking cessation with these two diseases as positive controls would lend evidence of validity to our findings of an association between smoking cessation and risk of knee replacement.…”

Section: Assessment Of Outcomesmentioning

confidence: 99%

Does smoking cessation increase risk of knee replacement? a general population-based cohort study

Zeng

Nguyen

et al. 2021

Osteoarthritis and Cartilage

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Section: Assessment Of Outcomesmentioning

confidence: 99%

Does smoking cessation increase risk of knee replacement? a general population-based cohort study

Zeng

Nguyen

et al. 2021

Osteoarthritis and Cartilage

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“…The death date recorded in the IMRD is linked to the NHS; thus, a change in vital status to “dead” is immediately updated in the person's electronic health record. The secondary outcomes were incident hypertension, 25 T2DM, 26 VTE (pulmonary embolism and deep vein thrombosis), CVD (myocardial infarction [MI] and stroke), 27 and any cancer (lung, breast, colorectal, prostate, head and neck, and other cancers) 28 identified by Read codes during the five‐year follow‐up period. VTE was defined as a recorded Read code of VTE with a prescription of anticoagulant medication.…”

Section: Methodsmentioning

confidence: 99%

Weight Loss Induced by Antiobesity Medications and All‐Cause Mortality Among Patients With Knee or Hip Osteoarthritis

Wei,

Hunter,

Lane

et al. 2023

Arthritis & Rheumatology

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ObjectiveThe current guidelines recommend weight loss for patients with overweight or obesity and knee or hip osteoarthritis (OA); however, there is a paucity of data on the relation of weight loss to death among patients with OA. We aimed to examine the relation of the rate of weight loss induced by antiobesity medications over one year to all‐cause mortality among patients with overweight or obesity and knee or hip OA.MethodsUsing the IQVIA Medical Research Database, we identified people with overweight or obesity and knee or hip OA. We emulated analyses of a hypothetical target trial to assess the effect of slow‐to‐moderate (2%–10%) or fast (≥10%) weight loss induced by the initiation of antiobesity medications within one year on all‐cause mortality and secondary outcomes over five years’ follow‐up.ResultsAmong 6,524 participants, the five‐year all‐cause mortality rates were 5.3%, 4.0%, and 5.4% for weight gain or stable, slow‐to‐moderate weight loss, and fast weight loss arms, respectively. Compared with the weight gain or stable arm, hazard ratios of all‐cause mortality were 0.72 (95% confidence interval [CI] 0.56–0.92) for the slow‐to‐moderate weight loss arm and 0.99 (95% CI 0.67–1.44) for the fast weight loss arm. We found dose–response protective effects of weight loss on incident hypertension, type 2 diabetes, and venous thromboembolism but a slightly higher risk of cardiovascular disease, albeit not statistically significant, in the fast rate of weight loss arm than in the weight gain or stable arm and no significant relations of weight loss to the risk of cancer.ConclusionIn this population‐based study, a slow‐to‐moderate, but not fast, rate of weight loss induced by antiobesity medications is associated with a lower risk of all‐cause mortality in people with overweight or obesity and knee or hip OA.image

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Risk for Cardiovascular Disease Early and Late After a Diagnosis of Giant-Cell Arteritis

Cited by 2 publications

References 4 publications

Does smoking cessation increase risk of knee replacement? a general population-based cohort study

Does smoking cessation increase risk of knee replacement? a general population-based cohort study

Weight Loss Induced by Antiobesity Medications and All‐Cause Mortality Among Patients With Knee or Hip Osteoarthritis

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