Risk for Suicidal Behavior Among Psoriasis Patients: A Nationwide Cohort Study

Wang, Shuhui; Wang, Jui; Chi, Ching‐Chi; Lin, Yu‐Sheng; Liao, Shih‐Cheng; Chen, Pei‐En; Tung, Tao‐Hsin

doi:10.1007/s40257-019-00489-9

Cited by 18 publications

(19 citation statements)

References 53 publications

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“…The results of the association between suicides and psoriasis in later studies are still contradictory: the risk of suicidal behavior in individuals with psoriasis was confirmed in Canada (97), but not in Taiwan (98).…”

Section: Suicidesmentioning

confidence: 97%

Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review

et al. 2022

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Psoriasis is a chronic autoimmune inflammatory disease that remains active for a long period, even for life in most patients. The impact of psoriasis on health is not only limited to the skin, but also influences multiple systems of the body, even mental health. With the increasing of literature on the association between psoriasis and extracutaneous systems, a better understanding of psoriasis as an autoimmune disease with systemic inflammation is created. Except for cardiometabolic diseases, gastrointestinal diseases, chronic kidney diseases, malignancy, and infections that have received much attention, the association between psoriasis and more systemic diseases, including the skin system, reproductive system, and oral and ocular systems has also been revealed, and mental health diseases draw more attention not just because of the negative mental and mood influence caused by skin lesions, but a common immune-inflammatory mechanism identified of the two systemic diseases. This review summarizes the epidemiological evidence supporting the association between psoriasis and important and/or newly reported systemic diseases in the past 5 years, and may help to comprehensively recognize the comorbidity burden related to psoriasis, further to improve the management of people with psoriasis.

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Section: Suicidesmentioning

confidence: 97%

Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review

et al. 2022

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“…For example, in a 2020 study of nearly 170,000 psoriasis patients and 170,000 healthy individuals, statistical processing of the data found no association between the presence of the disease and the risk of suicidal behavior. In addition, no such association was found in different severity groups of patients, with or without complications [21].…”

Section: Introductionmentioning

confidence: 83%

Peculiarities of expression indicators and accentuated personality traits in men with psoriasis without taking into account somatotype and in representatives of meso- and endo-mesomorphic somatotypes

Al-Qaraleh¹,

Степаненко²,

Kryvonis³

et al. 2021

Rep. of Vinnytsia Nation. Med. Univ.

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Annotation. Exacerbation and aggravation of psoriasis increases the chances of neurosis, depression, can significantly impair mental health through social stigma and leads to social isolation and maladaptation, a significant reduction in quality of life. Studying this problem from the standpoint of comparative assessment of the distribution of character accentuations in patients with different dermatoses can provide insight into how a certain level of adequacy of psychological adaptive response is associated with organic pathological process or genetically existing expression of certain traits. The aim of the study was to found the features of indicators of expression and features of accentuated personality traits in men with psoriasis without taking into account somatotype and in representatives of meso- and endo-mesomorphic somatotypes. Men aged 22 to 35 years, patients with psoriasis (n=100, including 32 with mild and 68 with severe course) at the Department of Skin and Venereal Diseases with a course of postgraduate education National Pirogov Memorial Medical University, Vinnytsya and Military Medical Clinical Center of the Central Region, conducted an anthropometric survey by V. V. Bunak Estimation of the expression and features of accentuated personality traits made according to G. Shmishek The reliability of the difference between the values between the independent quantitative values was determined using the U-Mann-Whitney test. In healthy subjects, taking into account and without taking into account the somatotype, it is seen that the type of physique did not significantly affect the severity of individual traits and their combinations in this group of people. With the increase in the course of psoriasis among subjects without somatotype, there is a decrease in the percentage of persons with hyperthymic and demonstrative and an increase – with emotional, pedantic, anxious, cyclothymic, excitable, dysthymic and exalted type of character accentuation; among patients of mesomorphic somatotype there is a decrease in the percentage of people with stuck and demonstrative and an increase – with emotional, pedantic, anxious, cyclothymic, excitable, dysthymic and exalted type of character accentuation; among patients of endo-mesomorphic somatotype there is a decrease in the percentage of people with hypertension and an increase – with stuck, demonstrative and excitable type of character accentuation. All this maintains a pathologically high level of affective tension, which disrupts the autonomic balance in the body, can be a pathogenic factor in the development of psychosomatic illness and leads to ineffective treatment of psoriasis.

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“…In the current study, we used the Longitudinal Health Insurance Database 2005 (LHID, 2005), which contains longitudinally linked data of 1 000 000 enrollees (approximately 5% of the population of Taiwan) randomly sampled from the 2005 Registry for Beneficiaries of the NHIRD. The LHID has been validated as a representative sample of the Taiwanese population with regard to age, sex, and income (Wang et al, 2020). The NHIRD employs data anonymization to ensure the confidentiality of enrollees; therefore, a full review of this study was waived by the Institution Review Board of Taipei Veterans General Hospital (IRB-TPEVGH No: 2015-11-001BC).…”

Section: Introductionmentioning

confidence: 99%

A population‐based study of the association between hemodialysis and cognitive impairment

Chien¹,

Lin

Huang

et al. 2020

Asia-Pacific Psychiatry

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Introduction: End-stage renal disease is a serious public health issue. The objective of this retrospective cohort study was to assess the association between hemodialysis and cognitive impairment, while controlling for age, sex, residence, and comorbidities. Methods: This study assesses the risk of cognitive impairment among a nationwide cohort of new hemodialysis patients derived from the NHIRD. Results: A total of 4330 patients were assigned to the dialysis group and 17 320 patients were assigned to the control group. A total of 2103 of the patients developed cognitive impairment within 2 years after the date of dialysis initiation. Patients who developed cognitive impairment were older (69.85 ± 11.56) than their counterparts who did not develop cognitive impairment (58.58 ± 14.77; P < .001). The logrank test of Kaplan-Meier analysis revealed a higher risk of cognitive impairment in the hemodialysis group than in the non-hemodialysis group (P < .001). The interval between dialysis initiation and the onset of cognitive impairment was 98.66 ± 46.39 months among non-dialysis subjects and 53.45 ± 41.90 months among dialysis subjects, and the between-group difference was significant (P < .001). The Cox Proportional Hazard Model revealed that after controlling for gender, age, residence, and comorbidities, hemodialysis was shown to have a significant impact on cognitive impairment (Hazard Ratio [HR]: 1.44; 95% confidence interval [CI]: 1.29-1.60). Furthermore, the risk of developing cognitive impairment increased with age (HR: 1.07; 95% CI: 1.06-1.08). Discussion: Hemodialysis was associated with cognitive impairment. There was a significant association between age and cognitive impairment, regardless of the comorbidities prior to hemodialysis. There was no evidence of an association between comorbidities and cognitive impairment after beginning hemodialysis.

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Risk for Suicidal Behavior Among Psoriasis Patients: A Nationwide Cohort Study

Cited by 18 publications

References 53 publications

Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review

Epidemiology of Psoriasis and Comorbid Diseases: A Narrative Review

Peculiarities of expression indicators and accentuated personality traits in men with psoriasis without taking into account somatotype and in representatives of meso- and endo-mesomorphic somatotypes

A population‐based study of the association between hemodialysis and cognitive impairment

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