Commentary on Seda et al. Comparative meta-analysis of prazosin and imagery rehearsal therapy for nightmare frequency, sleep quality, and posttraumatic stress. J Clin Sleep Med 2015;11:11-22.
James F. Pagel, MS, MDUniversity of Colorado School of Medicine, Pueblo, CO P osttraumatic stress disorder (PTSD) is arguably the most physiologically dangerous of the diagnoses addressed by the fi eld of Sleep Medicine. Of major psychiatric and medical diagnoses, PTSD is associated with the highest risk for both successful and unsuccessful suicide attempts.1 For some at risk populations (e.g., psychiatrically hospitalized adolescent offspring of war-associated PTSD veterans), the prevalence of suicide attempts exceeds sixty percent.2 This risk of suicidal behavior exists independent of comorbid depression 3,4 and is present even when the symptoms of PTSD are subthreshold in meeting criteria for the full diagnosis.5 The personal and social tolls for PTSD extend beyond suicide. Individuals with PTSD are far more likely to engage in substance abuse and risk taking behaviors including aggressive driving.6,7 The social sequelae of PTSD include job loss, divorce, homelessness, as well as increased risks for child and domestic abuse, sexual assault, violent crime, and re-incarceration.
8PTSD is treated with a wide variety of medication and psychological therapies. The most commonly utilized approaches, based on governmental and military recommendations for therapy, include various approaches to exposure therapy coupled with antidepressant and antianxiety medication.9-11 Exposure therapy, as utilized in Critical Incidence Stress Debriefi ng (CISD), is the most commonly utilized behavioral therapy for PTSD. 11,12 Since, when applied acutely, CISD can lead to increased symptoms for some patients, the American Psychiatric Association has called into question its routine use.13 While this approach to therapy for PTSD has been shown to diminish PTSD symptomatology, none of the current therapies for PTSD have been shown to reduce the occurrence of PTSD when utilized acutely after trauma, or to reduce the chance that PTSD will become a lifelong disorder.14,15 For many severely traumatized individuals, symptoms of PTSD persist into extreme old age.
16Nightmares are the most commonly reported symptom of PTSD.17 Among therapists utilizing exposure therapy to treat PTSD, some have the perspective that nightmares of the traumatic experience may be therapeutic-a useful part of the re-experience approach to therapy. Based on this perspective, some overviews of PTSD diagnosis and therapy deemphasize the role of recurrent nightmares both as a symptom and as a component of the diagnosis.
18The fi eld of Sleep Medicine has suggested an alternative approach to treating PTSD: proposing that the recurrent nightmares of PTSD lead to insomnia and next-day waking distress that contributes to waking symptoms of PTSD.19 This approach fi ts with an overall perspective that treating insomnia in psychiatric disorders can have signifi cant benefi ts. This appa...