Risk of acute otitis media in relation to acute bronchiolitis in children

Gomaa, Mohamed; Galal, Osama; Mahmoud, Mahmoud S.

doi:10.1016/j.ijporl.2011.09.029

Cited by 18 publications

(7 citation statements)

References 18 publications

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“…Both acute otitis media (n = 4; 3.08%) and conjunctivitis (n = 4; 3.08%) were surprisingly rare manifestations in our study group with RSV infection. According to the data in the literature, AOM affects 24% to even 58% of patients (22)(23)(24)(25)(26). However, these are mainly prospective studies, with the observation period up to one year after the end of hospitalization, which may lead to a higher percentage of this manifestation than in our retrospective study.…”

Section: Discussionmentioning

confidence: 59%

Manifestations and Risk Factors in Children Hospitalized with Respiratory Syncytial Virus Infection

Kuczborska

Rustecka

Wawrzyniak

et al. 2020

Arch Pediatr Infect Dis

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Background: Acute lower respiratory infection (ALRI) is one of the main causes of morbidity and mortality in children under five years of age, and the respiratory syncytial virus (RSV) remains its leading etiological factor. Although RSV infections occur in all age groups, the most severe course is observed among children. The clinical manifestations include both mild upper respiratory infections and severe infections of the lower tract, such as bronchiolitis and pneumonia that can lead to hospitalization and severe complications, including respiratory failure. Objectives: The study aimed to evaluate the manifestations of RSV infection in hospitalized children younger than 18 months of age and predictors of disease severity, as well as their comparison with the same age group hospitalized due to ALRI of different etiology. Methods: A retrospective analysis was performed on medical records of 448 children hospitalized due to ALRI. The analysis was performed on the total study group and subgroups of children with positive and negative results of the nasal swab for RSV detection. In each group, clinical data, laboratory test results, and imaging results were analyzed. Results: The most common manifestation was pneumonia (n = 82; 63.08%). Otitis media was observed mainly in children under six months of age with lowered inflammatory markers (P < 0.05), conjunctivitis in those with a positive family history of allergies (P < 0.05), and pneumonia in children under six months of age, with lower blood oxygen saturation and inflammatory markers, features of acidosis, and fever-free course (P < 0.05). Respiratory failure affected 13 children (10%). However, no predictors of this complication were noted. Conclusions: As pneumonia was the most common manifestation in children with both RSV-positive and RSV-negative ALRI, it seems advisable to perform the imaging of the lungs on admission and carefully monitor the child’s condition during hospitalization. In both groups, special attention should be paid to the youngest children with low inflammatory markers on hospital admission, increased clinical symptoms, and family history of allergies. Nevertheless, widely known risk factors of RSV infection itself do not reflect the risk of developing pneumonia or respiratory failure in its course.

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Section: Discussionmentioning

confidence: 59%

Manifestations and Risk Factors in Children Hospitalized with Respiratory Syncytial Virus Infection

Kuczborska

Rustecka

Wawrzyniak

et al. 2020

Arch Pediatr Infect Dis

View full text Add to dashboard Cite

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“…172,173 Although acute otitis media (AOM) in infants with bronchiolitis may be attributable to viruses, clinical features generally do not permit differentiation of viral AOM from those with a bacterial component. 174 Two studies address the frequency of AOM in patients with bronchiolitis. Andrade et al 175 prospectively identified AOM in 62% of 42 patients who presented with bronchiolitis.…”

Section: Action Statement Profile Kasmentioning

confidence: 99%

Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis

Ralston¹,

Lieberthal²,

Meissner³

et al. 2014

Pediatrics

1,426

1,654

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This guideline is a revision of the clinical practice guideline, “Diagnosis and Management of Bronchiolitis,” published by the American Academy of Pediatrics in 2006. The guideline applies to children from 1 through 23 months of age. Other exclusions are noted. Each key action statement indicates level of evidence, benefit-harm relationship, and level of recommendation. Key action statements are as follows:

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“…Between 20% and 41% of children admitted with a primary diagnosis of RSV infection (AB or CAP) also present with AOM [51],[52]. Another study reported RSV infection present in 56% of AOM pediatric cases hospitalized between 3 and 18 months [53]. In children admitted for RSV infection in their first year of life, the risk of developing allergic rhino-conjunctivitis was significantly greater than among controls (39% vs. 15%) [41],[45],[95].…”

Section: Resultsmentioning

confidence: 99%

Social, economic, and health impact of the respiratory syncytial virus: a systematic search

et al. 2014

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BackgroundBronchiolitis caused by the respiratory syncytial virus (RSV) and its related complications are common in infants born prematurely, with severe congenital heart disease, or bronchopulmonary dysplasia, as well as in immunosuppressed infants. There is a rich literature on the different aspects of RSV infection with a focus, for the most part, on specific risk populations. However, there is a need for a systematic global analysis of the impact of RSV infection in terms of use of resources and health impact on both children and adults. With this aim, we performed a systematic search of scientific evidence on the social, economic, and health impact of RSV infection.MethodsA systematic search of the following databases was performed: MEDLINE, EMBASE, Spanish Medical Index, MEDES-MEDicina in Spanish, Cochrane Plus Library, and Google without time limits. We selected 421 abstracts based on the 6,598 articles identified. From these abstracts, 4 RSV experts selected the most relevant articles. They selected 65 articles. After reading the full articles, 23 of their references were also selected. Finally, one more article found through a literature information alert system was included.ResultsThe information collected was summarized and organized into the following topics: 1. Impact on health (infections and respiratory complications, mid- to long-term lung function decline, recurrent wheezing, asthma, other complications such as otitis and rhino-conjunctivitis, and mortality; 2. Impact on resources (visits to primary care and specialists offices, emergency room visits, hospital admissions, ICU admissions, diagnostic tests, and treatments); 3. Impact on costs (direct and indirect costs); 4. Impact on quality of life; and 5. Strategies to reduce the impact (interventions on social and hygienic factors and prophylactic treatments).ConclusionsWe concluded that 1. The health impact of RSV infection is relevant and goes beyond the acute episode phase; 2. The health impact of RSV infection on children is much better documented than the impact on adults; 3. Further research is needed on mid- and long-term impact of RSV infection on the adult population, especially those at high-risk; 4. There is a need for interventions aimed at reducing the impact of RSV infection by targeting health education, information, and prophylaxis in high-risk populations.Electronic supplementary materialThe online version of this article (doi:10.1186/s12879-014-0544-x) contains supplementary material, which is available to authorized users.

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Risk of acute otitis media in relation to acute bronchiolitis in children

Cited by 18 publications

References 18 publications

Manifestations and Risk Factors in Children Hospitalized with Respiratory Syncytial Virus Infection

Manifestations and Risk Factors in Children Hospitalized with Respiratory Syncytial Virus Infection

Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis

Social, economic, and health impact of the respiratory syncytial virus: a systematic search

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