Introduction
The risk of cancer in patients diagnosed with myotonic dystrophy (DM) is reported for the homogeneous Utah population.
Methods
Clinical data accessed from the largest Utah healthcare providers have been record-linked to the Utah Population Database (UPDB), a population-based resource also linked to the Utah Cancer Registry. Relative risks were estimated for 36 cancers of different types in 281 DM patients.
Results
Testicular cancer (RR=10.74; 95% CI: 1.91, 38.79), endometrial cancer (6.98; 1.24, 25.22), and Non-Hodgkins lymphoma (4.25; 1.16, 12.43) were all observed at significant excess in DM patients.
Discussion
This study confirms an overall increased risk of cancer in DM. Individuals diagnosed with DM might benefit from risk counseling.