Risk of cardiovascular disease in HIV-infected patients

S, Das

doi:10.1093/jac/dkp460

Cited by 17 publications

(16 citation statements)

References 10 publications

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“…These complications might be even more frequent in elderly patients with HIV. 14 Badiou et al 15 studied nontraditional cardiovascular risk factors, such as non-high-density lipoprotein (HDL) cholesterol, apolipoprotein B, triglycerides-to-HDL ratio, low-density lipoprotein (LDL) size, inflammation markers, and carotid intimamedia thickness in a cohort of 232 HIV-positive adults, of whom 80% were in ART. Secondarily, the researchers wanted to study the relationship of metabolic syndrome and carotid intima-media thickness.…”

Section: Common Problems In Elderly Hiv-infected Patientsmentioning

confidence: 99%

A Dedicated Screening Program for Geriatric HIV-Infected Patients Integrating HIV and Geriatric Care

Ruiz

Cefalu

Ogbuokiri

2010

Journal of the International Association of Physicians in AIDS

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Background: Clinicians caring for HIV-infected patients >60 years old encounter multiple clinical challenges. The use of a functional geriatrics screening for detection of significant comorbidities is important in this population. Methods: The geriatrics screening evaluated functional capabilities, depression, cognitive dysfunction, nutrition, mobility, medicines used, and interactions. Results: As of July 2009, 57 patients were screened (average age 62.6, 39 males and 18 females). A total of 17 patients (9 males and 8 females) were referred to the geriatrics/HIV program because of identified problems in multiple domains: 10 with cognitive dysfunction, 8 with problems in basic or instrumental activities of daily living, 6 with nutritional issues, 5 with depression, 5 with mobility problems, 4 with visual issues, and 2 with hearing difficulties. The average age was 62.9. Median CD4 count and viral load were 285 (15-714) cells/mm 3 and 30 505 copies/mL (0-407 697), respectively. Conclusions: The functional yearly screening of patients >60 years with HIV needs to be part of regular care of patients infected with HIV as multiple functional problems can be diagnosed and addressed.

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Section: Common Problems In Elderly Hiv-infected Patientsmentioning

confidence: 99%

A Dedicated Screening Program for Geriatric HIV-Infected Patients Integrating HIV and Geriatric Care

Ruiz

Cefalu

Ogbuokiri

2010

Journal of the International Association of Physicians in AIDS

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“…Each year, an estimated 1,000,000 Americans will experience new coronary attacks or silent myocardial infarctions (Roger et al, 2012). For people living with HIV (PLWH), the situation is even worse, as rates of CVD are approximately two-fold higher than age-matched people without HIV infection (Das, 2010; Kearney, Moore, Donegan, & Lambert, 2010). Increased rates have been attributed, at least in part, to metabolic problems associated with antiretrovirals, including hyperlipidemia and glucose-related abnormalities (Das, 2010; Kearney et al, 2010).…”

mentioning

confidence: 99%

Menthol Cigarettes and the Cardiovascular Risks of People Living With HIV

Míguez‐Burbano

Vargas

Quiros

et al. 2014

Journal of the Association of Nurses in AIDS Care

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The possibility that menthol cigarettes add to the deleterious cardiovascular effects of smoking has been barely discussed. Although cardiovascular diseases (CVD) are at the forefront of medical concerns of people living with HIV (PLWH), an important, yet unknown, issue for clinicians and public health authorities is whether use of menthol-flavored cigarettes heightens CVD risk factors. Our study aims to assess traditional (10-year risk using the Framingham Risk Model) and nontraditional CVD risk factors and to contrast the effects of menthol-flavored versus non-menthol flavored cigarettes on these risk factors. Compared to controls, menthol smokers were twice as likely to have hypertension. Users of menthol-flavored cigarettes had higher body mass index values, and increased risk of abdominal obesity. Multivariate analyses indicated that menthol smokers doubled the odds of having moderate to high CVD risk. This finding is highly significant given the widespread use of menthol-flavored cigarettes, particularly among women, minorities, and PLWH.

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“…The fear of debilitating cacheexia has vanished, and has been replaced at a rapid pace by obesity complications [15,16]. The challenges of HIV management can be even greater when considering that obesity can exacerbate other illness, such as CVD and osteoporosis, that are already more prevalent among PLWH [16,17]. For PLWH, rates of CVD are approximately two-fold higher than for age-matched people without HIV infection [17].…”

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confidence: 99%

“…The challenges of HIV management can be even greater when considering that obesity can exacerbate other illness, such as CVD and osteoporosis, that are already more prevalent among PLWH [16,17]. For PLWH, rates of CVD are approximately two-fold higher than for age-matched people without HIV infection [17]. More frequent reports have been published suggesting that hypertension is also increasing in PLWH [18,19].…”

mentioning

confidence: 99%