Risk of depression and other mental health disorders in women with polycystic ovary syndrome: a longitudinal study

Kerchner, Angela; Lester, Whitney S.; Stuart, Scott; Dokras, Anuja

doi:10.1016/j.fertnstert.2007.11.022

Cited by 195 publications

(152 citation statements)

References 24 publications

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“…Hormonal deviations and a negative physical image in these patients cause depression (10), therefore, the prevalence of depression in patients with PCOS is 40% (11). In one study, the prevalence of mild to moderate depression was reported as 23.9% and 25.3%, respectively (12).…”

Section: Introductionmentioning

confidence: 99%

The Effect of Cognitive Behavioral Therapy on Depression and Obesity in Women with Polycystic Ovarian Syndrome: A Randomized Controlled Clinical Trial

Abdollahi

Mirghafourvand

Kheyradin

et al. 2018

Iran Red Crescent Med J

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Background: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder that can cause mental and psychological manifestations such as depression in addition to medical aspects like obesity. Objectives: The aim of this study was to evaluate the effect of cognitive-behavioral therapy on body mass index (BMI) and depression in women with PCOS. Methods: This randomized controlled trial was conducted on 74 women in Saqez-Iran, 2017. Participants were assigned into 2 groups of intervention and control through blocked randomization. The intervention group received cognitive-behavioral therapy in 8 sessions of 45 to 60 minutes. Beck's depression questionnaire was completed and body mass index (BMI) was calculated before and 4 weeks after the end of intervention. ANCOVA test was used to analyze the data. Results: There was no significant difference between the 2 groups in terms of socio-demographic characteristics (P > 0.05). After intervention, the mean (SD) of depression score in the intervention group was 4.5 (3.9) and in the control group 16.5 (8.6). Based on the ANCOVA test and with adjusting the baseline values, the mean depression score of the intervention group significantly was lower than the control group (adjusted mean difference: -13.8; confidence interval 95% = -10.9 to -16.7; P < 0.001). In addition, after intervention, the mean (SD) of BMI in the intervention group was 27.3 (5.4) and in the control group it was 29.4 (5.5). The intervention group was significantly lower than the control group, based on the ANCOVA test with adjusting the baseline values (-0.6; -0.2 to -0.9; P < 0.001). Conclusions: Cognitive-behavioral therapy is effective in improving depression and decreasing BMI in women with PCOS. Therefore, it is recommended to use this therapeutic approach to improve the physical and psychological health of these women.

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Section: Introductionmentioning

confidence: 99%

The Effect of Cognitive Behavioral Therapy on Depression and Obesity in Women with Polycystic Ovarian Syndrome: A Randomized Controlled Clinical Trial

Abdollahi

Mirghafourvand

Kheyradin

et al. 2018

Iran Red Crescent Med J

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“…Prospective studies in perimenopausal women with PCOS have demonstrated higher incidence of type II diabetes [1][2][3][4][5]. According to various authors, PCOS patients are more likely to suffer from mood disorders and increased anxi-ety [6][7][8][9]. Most studies on the mental functioning of the affected women are comparative, estimating the incidence of mood disorders and anxiety level in PCOS patients and healthy controls.…”

Section: Introductionmentioning

confidence: 99%

Determinants of emotional problems and mood disorders in women with polycystic ovary syndrome

Głowińska

Zielona–Jenek²,

Pawelczyk³

et al. 2016

Ginekol Pol

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Objectives: The aim of the study was to assess the prevalence and severity of emotional problems among Polish women with polycystic ovary syndrome (PCOS) and seek factors which increase the risk of their occurrence. Material and methods:The study group consisted of 82 women (aged 18-48), who were diagnosed with PCOS based on the Rotterdam criteria. During hospitalization, the patients completed a number of questionnaires, providing their sociodemographic data and information concerning the inconvenience of disease-associated symptoms. The questionnaires included the Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), and Multidimensional Self-Esteem Inventory (MSEI). Data obtained during medical examinations (blood tests, transvaginal ultrasound, height and body mass measurements) were analyzed.Results: Out of 82 women, the results detected risk for depression in 42 (51.22%), mild depressive disorders in 32, moderate disorders in 8, and severe disorder in 2 patients. No statistically significant correlation between BDI or state anxiety and the level of the analyzed hormones, insulin resistance, or infertility treatment, was found. General self-esteem, trait anxiety, and marital status were associated with the occurrence of depression symptoms. BMI was associated with the level of state anxiety during hospitalization. Conclusions:Women with PCOS are at risk for mood and anxiety disorders. Disease-related somatic factors are not directly associated with the risk for disorder occurrence. However, severity of depression symptoms has been shown to be influenced by permanent psychological characteristics of the studied women, i.e. self-esteem, trait anxiety, and life situation (marital status). Therefore, it is recommended to include interviews about patient life situation and screening questionnaires for assessing depression into the diagnostic procedures in PCOS patients. Patients should be referred for a psychological or psychiatric consultation, if needed.

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“…Women with PCOS are frequently overweight and suffer from other symptoms of the metabolic syndrome, such as hyper-tension and type-2 diabetes. Approximately 10 to 57% of women with PCOS suffer from a depressive disorder and a further 25% from subclinical forms of depression (Tan et al, 2008;Kerchner et al, 2009;Rassi et al, 2010;Hart and Doherty, 2015). Moreover, 25 to 36% suffer from a bulimic syndrome (Morgan et al, 2008).…”

Section: Polycystic Ovary Syndrome (Pcos)mentioning

confidence: 99%

Mental Disorders and Female Infertility

Schweiger

Schweiger²,

Schweiger³

2018

AOP

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Approximately 5 to 10 % of women in their reproductive years are affected by infertility. Infertility in women has been associated with depression, bipolar disorder, anxiety, disturbed eating behavior, autism, psychotic disorders and autism. Part of the association between depression, anxiety and infertility can be explained by the emotional stress resulting from infertility. As mental disorders like depressive disorder or eating disorders are also prospectively associated with infertility, a bidirectional relationship is assumed. The paper discusses the theories about the mechanistic link between mental disorders and infertility. A special relationship may between mental disorders and the main causes of ovulatory infertility, hypothalamic amenorrhea and polycystic ovary disease. Pilot studies support the assumption that psychotherapy may constitute an important component in the treatment of infertility.

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Risk of depression and other mental health disorders in women with polycystic ovary syndrome: a longitudinal study

Cited by 195 publications

References 24 publications

The Effect of Cognitive Behavioral Therapy on Depression and Obesity in Women with Polycystic Ovarian Syndrome: A Randomized Controlled Clinical Trial

The Effect of Cognitive Behavioral Therapy on Depression and Obesity in Women with Polycystic Ovarian Syndrome: A Randomized Controlled Clinical Trial

Determinants of emotional problems and mood disorders in women with polycystic ovary syndrome

Mental Disorders and Female Infertility

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