2023
DOI: 10.1007/s12094-023-03312-4
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Risk of endometrial cancer after RRSO in BRCA 1/2 carriers: a multicentre cohort study

Helena Pla-Juher,
Marta Pardo,
Àngel J. Izquierdo
et al.

Abstract: Objective To know the risk of endometrial cancer (EC) in a population of women with BRCA 1/2 pathogenic or likely pathogenic variants after risk-reducing salpingo-oophorectomy (RRSO). Methods The study cohort included data from 857 women with BRCA mutations who underwent RRSO visited four hospitals in Catalonia, Spain, from January 1, 1999 to April 30, 2019. Standardized incidence ratio (SIR) of EC was calculated in these patients using data from a regiona… Show more

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