Background
Healthcare workers (HCWs) and ethnic minority groups are at increased risk of COVID[ndash]19 infection and adverse outcome. Severe acute respiratory syndrome coronavirus[ndash]2 (SARS[ndash]CoV[ndash]2) vaccination is now available for frontline UK HCWs; however, demographic/occupational associations with vaccine uptake in this cohort are unknown. We sought to establish these associations in a large UK hospital workforce.
Methods
We conducted cross[ndash]sectional surveillance examining vaccine uptake amongst all staff at University Hospitals of Leicester NHS Trust. We examined proportions of vaccinated staff stratified by demographic factors, occupation and previous COVID-19 test results (serology/PCR) and used logistic regression to identify predictors of vaccination status after adjustment for confounders.
Findings
We included 19,044 HCWs; 12,278 (64.5%) had received SARS-CoV-2 vaccination. Compared to White HCWs (70.9% vaccinated), a significantly smaller proportion of ethnic minority HCWs were vaccinated (South Asian 58.5%, Black 36.8% p<0.001 for both). After adjustment, factors found to be negatively associated with vaccine uptake were; younger age, female sex, increasing deprivation and belonging to any non-White ethnic group (Black: aOR0.30, 95%CI 0.26[ndash]0.34, South Asian:0.67, 0.62[ndash]0.72). Allied health professionals and administrative/executive staff were more likely to be vaccinated than doctors.
Interpretation
Ethnic minority HCWs and those from more deprived areas as well as those from particular occupational groups are less likely to take up SARS[ndash]CoV[ndash]2 vaccination. These findings have major implications for the delivery of SARS[ndash]CoV[ndash]2 vaccination programmes, in HCWs and the wider population and should inform the national vaccination programme to prevent the disparities of the pandemic from widening.
Funding
NIHR, UKRI/MRC