Risk of human health by particulate matter as a source of air pollution -Comparison with tobacco smoking-

Enomoto, Makoto; Tierney, William J.; K, Nozaki

doi:10.2131/jts.33.251

Cited by 24 publications

(14 citation statements)

References 87 publications

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“…Tobacco and tobacco products are widely consumed throughout the world, and the pollution and health hazards caused by smoking are a serious problem [1]. Cigarette smoke contains more than 5200 components [2], among them 69 carcinogens have been identified and several are tumor promoters or co-carcinogens.…”

Section: Introductionmentioning

confidence: 99%

Hierarchical Composites to Reduce N-Nitrosamines in Cigarette Smoke

Cao

Yue

et al. 2015

Materials

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In order to reduce the harmful constituents in cigarette smoke, two hierarchical composites were synthesized. Based on, zeolites HZSM-5 or NaY fragments were introduced into the synthetic system of mesoporous silica SBA-15 or MCM-41 and assembled with the mesoporous materials. These porous composites combine the advantages of micro- and mesoporous materials, and exhibit higher effects than activated carbon on reducing tobacco specific nitrosamines (TSNA) and some vapor phase compounds in smoke.

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Section: Introductionmentioning

confidence: 99%

Hierarchical Composites to Reduce N-Nitrosamines in Cigarette Smoke

Cao

Yue

et al. 2015

Materials

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“…Air pollution with emissions and transport industries, and water and soil with heavy metals above the maximum permissible concentrations and evolution of other exogenous and endogenous risk factors lead to an increase in illness, especially cancer pathology, and in particular cancer of the larynx (Enomoto et al, 2008;Poirier, 2012). Environmental carcinogens and materials causing irritation are well known to be aetiological factors for laryngeal cancer.…”

Section: Introductionmentioning

confidence: 99%

Epidemiological Evaluation of Laryngeal Cancer Incidence in Kazakhstan for The Years 1999-2009

Igissinov¹,

Zatoskikh²,

Moore³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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The purpose was to provide a descriptive epidemiological assessment of the incidence of cancer of the larynx in Kazakhstan and spatial evaluation with gender characteristics. Thgis retrospective study covered all new cases of laryngeal cancer in 11 years (1999-2009). The total number was 4,967 cases, 4,535 (91.3%) in males and 432 (8.7%) in women, with a ratio of 10.5:1. The higher incidence in men compared to women was evident in all age groups, the differences being statistically significant (p<0.05). At the same time revealed a unimodal growth with age, peaking at 70 years and older both sexes. In the dynamics, incidence rates of laryngeal cancer demonstrated a tendency to decrease, in women (T=−6.7%) this being more pronounced than in men (T=−3.3%). Levels were determined to produce cartograms of cancer of the larynx for male and female populations, clear geographical variation being evidenced. The data are discussed with reference to possible risk factors.

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“…A Diminuição da VFC está associada ao risco aumentado de mortalidade na população em geral e do desenvolvimento de eventos cardíacos não fatais (Dekker et al, 1997 A exposição crônica por MP 2,5 e SO x é um fator de risco importante nos casos de mortalidade por doenças cardiopulmonares e câncer no pulmão (Enomoto et al, 2008). Mesmo se a inalação de MP 2,5 ocorra durante alguns minutos ou horas, existe a possibilidade de IAM, isquemia cardíaca, arritmias, insuficiência cardíaca e morte súbita (Brook, 2008 synthase) e a consequente diminuição na produção de óxido nítrico favorecendo o efeito constritor pela endotelina-1.…”

Section: Materials Particuladounclassified

Efeitos cardiopulmonares da exposição ao material particulado fino (MP2,5) proveniente do concentrador de partículas ambientais (CPA) na hipertrofia ventricular esquerda de ratos wistar

Belotti¹

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Aos amigos Luiz Afonso Pires, Mac Gayver da Silva Castro e RobsonSeriani pela amizade e companheirismo durante o todo o período de estudo e divertimento.Ao Guilherme, Gabriel e Laís minha sincera gratidão pela ajuda e dedicação que foram oferecidas neste trabalho. Epidemiological and experimental studies have consistently shown that both short-and long-term exposures to air pollution are associated with a variety of cardiovascular diseases. Air pollution is composed by a mixture of noxious substance including particles and gases. The cardiovascular adverse effects are more commonly attributed to particles and toxicological experiments have demonstrated several mechanisms by which particle exposure may trigger these effects. In this study we investigated the effects of time (7, 15 and 21 days) of exposure to concentrated ambient particles (dose = 600 µg/m³) on morphofunctional parameters of the heart in normal and rats with left ventricular hypertrophy (LVH) induced by isoproterenol (nonselective β-adrenergic agonist with direct action) (1.2 mg/kg). The use of LVH rats was motivated by the fact that individuals with cardiovascular diseases are considered at higher risk for effect of ambient PM. Our data have shown that time is an important factor on the magnitude of the effects of concentrated ambient particles on heart function and morphology, as shown by increased HRV (heart rate variability), decreased heart rate and increased volume of connective tissue in left ventricle myocardium. LVH rats presented similar outcomes but more severe effects on the heart which included decreased blood pressure and increased cardiomyocyte hypertrophy compared to non-exposed LVH rats. In conclusion, our results corroborate with previous findings that particulate air pollution induces changes in the autonomic control of the heart and that individual with previous cardiovascular disease are more affected than normal ones. We have further shown that concentrated ambient particles are capable of inducing changes in the microstructure of the myocardium depending on accumulated dose of exposure. SUMÁRIO Lista de quadros

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Risk of human health by particulate matter as a source of air pollution -Comparison with tobacco smoking-

Cited by 24 publications

References 87 publications

Hierarchical Composites to Reduce N-Nitrosamines in Cigarette Smoke

Hierarchical Composites to Reduce N-Nitrosamines in Cigarette Smoke

Epidemiological Evaluation of Laryngeal Cancer Incidence in Kazakhstan for The Years 1999-2009

Efeitos cardiopulmonares da exposição ao material particulado fino (MP2,5) proveniente do concentrador de partículas ambientais (CPA) na hipertrofia ventricular esquerda de ratos wistar

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