Risk of Leukemia in Children Living Near High-Voltage Transmission Lines

Li, Chung‐Yi; Lee, Wei-Chin; Lin, Ruey S.

doi:10.1097/00043764-199802000-00010

Cited by 24 publications

(15 citation statements)

References 11 publications

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“…Epidemiological studies suggest a connection between ELF-EMF exposure and certain diseases. Such exposure may play a role in the development of childhood leukaemia [Li et al, 1998] or in the progress of Alzheimer's disease [Harmanci et al, 2003]. ELF-EMF exposure may stimulate the secretion of b-amyloid peptide in exposed cultured neuroglioma cells [Del Giudice et al, 2007].…”

Section: Introductionmentioning

confidence: 99%

Changes in synaptic efficacy and seizure susceptibility in rat brain slices following extremely low‐frequency electromagnetic field exposure

Varró

Szemerszky

Bárdos

et al. 2009

Bioelectromagnetics

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The effects of electromagnetic fields (EMFs) on living organisms are recently a focus of scientific interest, as they may influence everyday life in several ways. Although the neural effects of EMFs have been subject to a considerable number of investigations, the results are difficult to compare since dissimilar exposure protocols have been applied on different preparations or animals. In the present series of experiments, whole rats or excised rat brain slices were exposed to a reference level-intensity (250-500 microT, 50 Hz) EMF in order to examine the effects on the synaptic efficacy in the central nervous system. Electrophysiological investigation was carried out ex vivo, on neocortical and hippocampal slices; basic synaptic functions, short- and long-term plasticity and seizure susceptibility were tested. The most pronounced effect was a decrease in basic synaptic activity in slices treated directly ex vivo observed as a diminution in amplitude of evoked potentials. On the other hand, following whole-body exposure an enhanced short- and long-term synaptic facilitation in hippocampal slices and increased seizure susceptibility in neocortical slices was also observed. However, these effects seem to be transient. We can conclude that ELF-EMF exposure exerts significant effects on synaptic activity, but the overall changes may strongly depend on the synaptic structure and neuronal network of the affected region together with the specific spatial parameters and constancy of EMF.

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Section: Introductionmentioning

confidence: 99%

Changes in synaptic efficacy and seizure susceptibility in rat brain slices following extremely low‐frequency electromagnetic field exposure

Varró

Szemerszky

Bárdos

et al. 2009

Bioelectromagnetics

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“…Thus, we may compare the present results to those from studies using distance from homes to a HVPL 6,7,[15][16][17][18] or magnetic fields calculated based on the distance. [4][5][6][7]19 Of these, two studies showed a clear association with reasonable statistical confidence.…”

Section: Case Ascertainmentmentioning

confidence: 95%

“…In Sweden, Feychting and Ahlbom 6 reported an increased risk of childhood leukemia associated with living within 50 m of HVPLs (odds ratio: 2.9; 95% CI: 1.0-7.3). In Taiwan, Li et al 18 found an increased risk of leukemia among children who resided within 100 m of HVPLs (standardized incidence ratio: 2.43; 95% CI: 0.98-5.01). The risk estimate Applying small area analysis, we found an increased risk of childhood hematological malignancies among children who lived in districts near HVPLs.…”

Section: Case Ascertainmentmentioning

confidence: 99%

Residential Proximity to High-Voltage Power Lines and Risk of Childhood Hematological Malignancies

Mizoue

Onoe

Moritake

et al. 2004

Journal of Epidemiology

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BACKGROUND: Epidemiologic studies of electromagnetic fields and childhood cancers have focused on home exposure. The authors investigated whether residence in districts near high-voltage power lines is associated with childhood hematological malignancies, using small area analysis. METHODS: Among 50,000 children in a city in Japan, 14 cases aged younger than 15 years were diagnosed with these malignancies in the period from 1992 through 2001. A total of 294 districts constituting this city were classified according to their proximity to high-voltage power lines (either 66 kV or 220 kV). Mantel-Haenszel rate ratio is used to calculate incidence rate ratio and its 95% confidence interval (CI). RESULTS: Compared to districts of which no area fell within 300 m of high-voltage power lines, districts in which at least 50% of the area fell within 300 m of high-voltage power lines demonstrated an increased risk (incidence rate ratio: 2.2; 95% CI: 0.5-9.0). The association was strengthened for homes in which patients had resided for the longest interval of their lives (incidence rate ratio: 3.4; 95% CI: 0.9-13.2). Point-in-time measurements showed no increase in magnetic field levels for patient homes in districts near the lines. CONCLUSION: An increased, albeit nonsignificant, risk of childhood hematological malignancies associated with residential proximity to high-voltage power lines warrants further investigations.

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“…Most suggested increased risk associated to higher exposure, although, in general, 95% Confidence Intervals had null risk in� cluded 41,53,54,55,56,57 .…”

Section: Childhood Leukemiamentioning

confidence: 99%

Campos magnéticos de frequência extremamente baixa e efeitos na saúde: revisão da literatura

Marcílio

Habermann

2009

Rev. bras. epidemiol.

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Este estudo foi financiado pela ANEEL -Agência Nacional de Energia Elétrica. AbstractSince an epidemiologic report, in 1979, showed an association between childhood leukemia and exposure to magnetic fields, concerns over the subject have grown, and several other studies have been published. The main goal of this literature review is to present the methods of exposure assess� ment and the main difficulties in measuring exposure, and also to report the results of epidemiological studies published along the past ten years. The lack of biophysical mechanisms explaining the interaction between magnetic fields and health, and the difficulties regarding exposure assessment have been the main obstacles of research in this area. Leukemia and brain tumors are the most evaluated outcomes. Childhood leukemia has been the most consistently outcome associated with magnetic field exposure. Recent studies have also shown an association between magnetic fields and amyotrophic lateral sclerosis.

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Risk of Leukemia in Children Living Near High-Voltage Transmission Lines

Cited by 24 publications

References 11 publications

Changes in synaptic efficacy and seizure susceptibility in rat brain slices following extremely low‐frequency electromagnetic field exposure

Changes in synaptic efficacy and seizure susceptibility in rat brain slices following extremely low‐frequency electromagnetic field exposure

Residential Proximity to High-Voltage Power Lines and Risk of Childhood Hematological Malignancies

Campos magnéticos de frequência extremamente baixa e efeitos na saúde: revisão da literatura

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