Abstract:This study failed to detect any relationship between lung cancer and exposure to iron, chromium, nickel and/or their compounds. High and statistically significant relative risks, along with increasing trends, were observed for simultaneous exposure to PAHs and silica.
“…The observed low mortality is very similar to that reported in other industries in France (Moulin et al 2000). Although this study is on the whole quite powerful, it lacked statistical power and precision to assess specific causes of death, particularly in view of the average age (48 years old).…”
This cohort study does not support previous observations that cement workers are at higher risk of cancer mortality than the general population. The length of follow-up should be increased, and specific exposures deserve analysis.
“…The observed low mortality is very similar to that reported in other industries in France (Moulin et al 2000). Although this study is on the whole quite powerful, it lacked statistical power and precision to assess specific causes of death, particularly in view of the average age (48 years old).…”
This cohort study does not support previous observations that cement workers are at higher risk of cancer mortality than the general population. The length of follow-up should be increased, and specific exposures deserve analysis.
“…A nonsignificantly increased risk of oral and pharyngeal cancer was found in the two studies of coke workers (Hurley et al 1983;Swaen et al 1991), but studies of foundry workers (Hoshuyama et al 2006;Moulin et al 2000b;Sherson et al 1991;Sorahan et al 1994) did not show results consistent enough for a definitive conclusion. Evanoff et al (1993) studied a cohort of chimney sweeps and found an increased incidence of cancer of OC and pharynx.…”
Future investigations should overcome common weaknesses of past studies, in terms of sample size, characterization of exposure, and classification of cancer sites.
“…Although numerous studies suggest that there is an association between exposure to iron fumes or dust at work and lung cancer risk (11)(12)(13)(14), the possible effect from other agents in simultaneous exposure could not be ruled out completely. Exposure to iron fumes or dust and welding fumes is associated because the main constituent of welding fumes is iron and its compounds.…”
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