Risk of Malignancy Index 2 in Preoperative Evaluation of Ovarian Masses and Its Correlation With Histopathology

Abstract

OBJECTIVETo evaluate the accuracy of risk malignancy index 2 in discriminating between benign and malignant ovarian masses preoperatively in gynaecologic practice and its correlation with histopathological report. METHODSThis was a prospective study conducted in a tertiary care hospital from consecutive 90 women with ovarian masses scheduled for surgery at Gynaecology Department between November 2013 and October 2015. After thorough history and clinical examination of patients, preoperative ultrasound findings, serum CA-125 levels and menopausal status were noted and RMI2 was calculated. RESULTSIncidence of benign neoplasm was 94.45%, while that of malignant neoplasm was 5.55%. When three parameters were separately compared with RMI2; RMI2 outperformed the others. After application of chi square test (x 2 ), 'p' value was found to be highly significant for RMI2, USG score and CA-125. CONCLUSIONRMI2 is more accurate in discrimination between malignant and benign ovarian masses than CA-125, USG and Menstrual score alone. It can be introduced easily into clinical practice to facilitate the selection of patients appropriate for primary surgery. KEYWORDSRMI2, Ovarian masses, USG score and CA-125. HOW TO CITE THIS ARTICLE:Thakare S, Dube A, Wankhede S. Risk of malignancy index 2 in preoperative evaluation of ovarian masses and its correlation with histopathology.