Risk of second primary in situ and invasive melanoma in a Dutch population‐based cohort: 1989–2008

Abstract

This study shows significantly increased long-term risks (both relative and absolute) of developing a second invasive melanoma after a first melanoma (invasive and in situ), and might serve as a basis for follow-up guidelines.

Burden of disease due to cutaneous melanoma has increased in the Netherlands since 1991

“…8 Furthermore, the risk for a second primary melanoma remains elevated up to 20 years after diagnosis. 35 Considering the risk of recurrence, second primary cancer and the impact on patients' lives, melanoma may be regarded as a chronic disease. For this reason, we assigned a disability weight after 5 years of follow-up care (0Á03), which resulted in higher DALY rates than those estimated for Europe, and we calculated the YLM without a disability weight.…”

Skin Examination Practices Among Melanoma Survivors and Their Children

“…Following successful treatment of the disease, melanoma survivors remain at elevated risk for recurrence and development of new melanomas [2]. Relative to many other cancers, younger and middle-aged adults bear a disproportionate disease burden, with more than half of melanoma cases diagnosed before the age of 65.…”

Comprehensive capture of cutaneous melanoma by the Ontario Cancer Registry: validation study using community pathology reports

“…Second, OCR registers only the first incident melanoma diagnosis for a given patient. This method of dealing with multiple primary tumors is particularly problematic for melanoma, given that 3-9 % of patients develop a second primary melanoma [21][22][23][24], and that previous melanoma is an independent risk factor for a subsequent primary melanoma [25][26][27]. For patients with multiple primary melanomas whose first melanoma diagnosis preceded the LifeLabs pathology report, the LifeLabs report would not have been registered as a distinct melanoma diagnosis in OCR.…”