Risk of stroke and atrial fibrillation after radiofrequency catheter ablation of typical atrial flutter

Tomson, Todd T.; Kapa, Suraj; Bala, Rupa; Riley, Michael P.; Lin, David; Epstein, Andrew E.; Deo, Rajat; Dixit, Sanjay

doi:10.1016/j.hrthm.2012.07.013

Cited by 48 publications

(45 citation statements)

References 21 publications

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“…It has been reported before that patients with typical AFL undergoing CTI ablation remain at a markedly elevated risk for developing new‐onset AF afterward ,. Our prospective study data confirm these prior observations.…”

Section: Discussionsupporting

confidence: 90%

Pulmonary Vein Isolation to Reduce Future Risk of Atrial Fibrillation in Patients Undergoing Typical Flutter Ablation: Results from a Randomized Pilot Study (REDUCE AF)

Mohanty

Natale

Mohanty

et al. 2015

Cardiovasc electrophysiol

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Section: Discussionsupporting

confidence: 90%

Pulmonary Vein Isolation to Reduce Future Risk of Atrial Fibrillation in Patients Undergoing Typical Flutter Ablation: Results from a Randomized Pilot Study (REDUCE AF)

Mohanty

Natale

Mohanty

et al. 2015

Cardiovasc electrophysiol

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“…The observed hazard ratio between the ablated and non-ablated groups, however, was small and did not reach statistical significance. Our findings are in agreement with a recent study from a single, experienced academic center that reported substantial AF and stroke risk after AFL ablation [16]. This prior investigation, however, had comparatively few events and used historic controls to identify the heightened risk of these post-ablation outcomes.…”

Section: Discussionsupporting

confidence: 91%

Healthcare Utilization and Clinical Outcomes after Catheter Ablation of Atrial Flutter

2014

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Atrial flutter ablation is associated with a high rate of acute procedural success and symptom improvement. The relationship between ablation and other clinical outcomes has been limited to small studies primarily conducted at academic centers. We sought to determine if catheter ablation of atrial flutter is associated with reductions in healthcare utilization, atrial fibrillation, or stroke in a large, real world population. California Healthcare Cost and Utilization Project databases were used to identify patients undergoing atrial flutter ablation between 2005 and 2009. The adjusted association between atrial flutter ablation and healthcare utilization, atrial fibrillation, or stroke was investigated using Cox proportional hazards models. Among 33,004 patients with a diagnosis of atrial flutter observed for a median of 2.1 years, 2,733 (8.2%) underwent catheter ablation. Atrial flutter ablation significantly lowered the adjusted risk of inpatient hospitalization (HR 0.88, 95% CI 0.84–0.92, p<0.001), emergency department visits (HR 0.60, 95% CI 0.54–0.65, p<0.001), and overall hospital-based healthcare utilization (HR 0.94, 95% CI 0.90–0.98, p = 0.001). Atrial flutter ablation was also associated with a statistically significant 11% reduction in the adjusted hazard of atrial fibrillation (HR 0.89, 95% CI 0.81–0.97, p = 0.01). Risk of acute stroke was not significantly reduced after ablation (HR 1.09, 95% CI 0.81–1.45, p = 0.57). In a large, real world population, atrial flutter ablation was associated with significant reductions in hospital-based healthcare utilization and a reduced risk of atrial fibrillation. These findings support the early use of catheter ablation for the treatment of atrial flutter.

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“…При ретроспективном анализе историй болезни па-циентов, наблюдаемых с 2002 по 2010 г., T. Tomson и со-авт. [48] показали, что после удачно проведенной проце-дуры РЧА типичного ТП возрастает риск возникновения ФП, и это является единственным фактором риска разви-тия инсульта. В исследование были включены 126 паци-ентов.…”

Section: нарушения ритма сердцаunclassified

Catheter radiofrequency ablation in atrial fibrillation and flutter management in patients with comorbidities

Kachanova¹,

Marfunina²,

Новикова³

et al. 2016

Kardiol. serdechno-sosud. khir.

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Risk of stroke and atrial fibrillation after radiofrequency catheter ablation of typical atrial flutter

Cited by 48 publications

References 21 publications

Pulmonary Vein Isolation to Reduce Future Risk of Atrial Fibrillation in Patients Undergoing Typical Flutter Ablation: Results from a Randomized Pilot Study (REDUCE AF)

Pulmonary Vein Isolation to Reduce Future Risk of Atrial Fibrillation in Patients Undergoing Typical Flutter Ablation: Results from a Randomized Pilot Study (REDUCE AF)

Healthcare Utilization and Clinical Outcomes after Catheter Ablation of Atrial Flutter

Catheter radiofrequency ablation in atrial fibrillation and flutter management in patients with comorbidities

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