Risk of Type 2 Diabetes Among Individuals with Excess Weight: Weight Trajectory Effects

Owora, Arthur H.; Allison, David B.; Zhang, Xuan; Gletsu‐Miller, Nana; Gadde, Kishore M.

doi:10.1007/s11892-022-01486-9

Curr Diab Rep

2022

DOI: 10.1007/s11892-022-01486-9

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Risk of Type 2 Diabetes Among Individuals with Excess Weight: Weight Trajectory Effects

Arthur H. Owora

David B. Allison

Xuan Zhang

et al.

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Cited by 2 publications

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Are treatment options used for adult-onset type 2 diabetes mellitus (equally) available and effective for children and adolescents?

Krnic,

Sesa,

Mrzljak

et al. 2024

World J Diabetes

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Youth-onset type 2 diabetes mellitus (T2DM), influenced by an increase in obesity, is a rising problem worldwide. Pathophysiological mechanisms of this early-onset T2DM include both peripheral and hepatic insulin resistance, along with increased hepatic fasting glucose production accompanied by inadequate first and second-phase insulin secretion. Moreover, the incretin effect is reduced. The initial presentation of type 2 diabetes can be dramatic and symptoms may overlap with those of type 1 diabetes mellitus. Therefore, immediate therapy should address hyperglycemia and associated metabolic derangements irrespective of ultimate diabetes type, while further therapy adjustments are prone to patients’ phenotype. New agents with proven glycemic and beyond glycemia benefits, such as Glucagon-like polypeptide 1 receptor agonists and Sodium-glucose cotransporter-2 inhibitors, used in the adult population of T2DM patients, might become increasingly important in the treatment armamentarium. Moreover, metabolic surgery is an option for markedly obese (body mass index > 35 kg/m2) children and adolescents suffering from T2DM who have uncontrolled glycemia and/or serious comorbidities when lifestyle and pharmacologic interventions fail. In this mini-review, we will discuss the potential of treatment options considering new data available from randomized control trials, including individuals with adult-onset type diabetes mellitus.

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Are treatment options used for adult-onset type 2 diabetes mellitus (equally) available and effective for children and adolescents?

Krnic,

Sesa,

Mrzljak

et al. 2024

World J Diabetes

View full text Add to dashboard Cite

show abstract

Food consumption, type 2 diabetes mellitus and weight status among adults in the Lingwala Health Zone, Kinshasa, the Democratic Republic of the Congo

Sikayako Kikwayabo,

Kekemb Bukele,

Mupenda

2023

Journal of Global Health Economics and Policy

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Background With the epidemiological transition, non-communicable diseases are now a major problem, including in the Democratic Republic of the Congo, where the population’s eating habits are constantly changing, with obesity and hyperglycemia in increase. This study aimed to examine the association between dietary habits, factors associated with type 2 diabetes mellitus and weight status in people over 18 years of age in Kinshasa, Democratic Republic of the Congo. Methods In a descriptive cross-sectional study among 182 adults, selected using multistage probability sampling (Health Zone, Health Area, Household, Individual), a structured questionnaire was used to collect behavioural data. The World Health Organization (WHO) Anthro plus was used to calculate body mass index. Descriptive statistics were completed with the Chi2 test, whereas a multivariate analysis used correlation with 95% confidence interval (CI) with eating habits, glycemic status and weight status as major variables. Results There were 68.8% respondents with high weight trouble (44.4% overweight and 24.0% obese). Up to 14.8% respondents were both overweight and hyperglycemic. Only 14.8% respondents reading labels of paid products was associated with glycemic status (P<0.05). Up to 61.5% respondents reported preparing own food, 54.4% eating alone, 96.7% consuming oils, sugar and sweet products, 92.9% consuming milk and its derivatives, 85.2% meat and fish, and 82.4% consumed fruits. However, none of these parameters was significantly associated with glycemic status Conclusions Stakeholders, including MoH, community, and civil society need to partner in raising awareness for changing behavior and eating habits such as mindful eating, balanced diet and regular eating.

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Risk of Type 2 Diabetes Among Individuals with Excess Weight: Weight Trajectory Effects

Cited by 2 publications

References 82 publications

Are treatment options used for adult-onset type 2 diabetes mellitus (equally) available and effective for children and adolescents?

Are treatment options used for adult-onset type 2 diabetes mellitus (equally) available and effective for children and adolescents?

Food consumption, type 2 diabetes mellitus and weight status among adults in the Lingwala Health Zone, Kinshasa, the Democratic Republic of the Congo

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