Oyster culture activity along the eastern Amazon mangrove coast in Pará state, Brazil, was evaluated using socio‐economic data to support its management and future development. Between 2013 and 2014, surveys were carried out in the region's seven oyster culture associations through interviews with the president of each association as well as with 56 members (72% of the total). Further data up to 2016 were obtained from annual reports of the Serviço Brasileiro de Apoio às Micro e Pequenas Empresas in Pará and the Instituto Brasileiro de Geografia e Estatística. Two associations stand out from the rest due to their larger on‐growing areas and total production in 2013. However, smaller associations are more efficient with higher production per unit area. Currently, oyster culture in Pará provides an alternative source of income for 80 families, where total production has increased from 8.25 tons in 2013 to 41.8 tons in 2016. Although associations have grown in number since 2006, along with increased capacity and production due to government assistance, in comparison with other regions of Brazil, they need to be better organized internally, including regular monitoring of growth, production and environmental variables, development of depuration facilities and improved distribution and presentation of products. Diversification of seed supply among different locations is desirable. There should also be less dependence on public funding and more partnerships with private enterprise, as well as active coparticipation in the development of legislation and public policies regulating both oyster culture and protection of natural oyster beds.