Risk stratification of Asian patients with heart failure and reduced ejection fraction: the effectiveness of the Echo Heart Failure Score

Bosch, Lena; Carluccio, Erberto; Coiro, Stefano; Gong, Lingli; Sim, David; Yeo, Daniel; Jaufeerally, Fazlur; Leong, Kui Toh Gerard; Ong, Hean Yee; Pin, Ng Tze; Richards, A. Mark; Arslan, Fatih; Ling, Lieng Hsi; Lam, Carolyn S.P.; Ambrosio, Giuseppe

doi:10.1002/ejhf.922

Cited by 7 publications

(2 citation statements)

References 16 publications

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“…Nowadays, no echocardiographic prognostic score has had some application in HFpEF, as opposed to HFrEF, for which both echo score and prognostic models have been proposed 23,24 .…”

Section: Comparison With Other Prognostic Scores In Heart Failure Wit...mentioning

confidence: 99%

Validation of the MEDIA echo score for the prognosis of heart failure with preserved ejection fraction

et al. 2022

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Background: There is currently no widely used prognostic score in heart failure with preserved ejection fraction (HFpEF). The MEDIA echo score, including four variables [pulmonary arterial systolic pressure >40mmHg, inferior vena cava collapsibility index <50%, average E/e' >9, and lateral mitral annular s' <7cm/s] has been proposed as a useful risk stratification tool. This study aimed at further validating the MEDIA echo score in both hospitalised and ambulatory HFpEF patients.Methods: the MEDIA echo score ranges from 0 to 4 (each criterion score 1 point). The associations between MEDIA echo score and cardiovascular outcomes were assessed in two independent HFpEF cohorts, namely patients hospitalised for worsening HFpEF (N=242, mean age 78±11) and stable ambulatory HFpEF patients (N=72, mean age 65±8).Results: Using multivariable Cox models, in the worsening HFpEF cohort, patients with a MEDIA echo score 3-4 displayed a significant increased risk of death (HR 2.10, 95%CI 1.02-4.33, P=0.043, score 0-1 as reference). In the ambulatory HFpEF cohort, patients with a MEDIA echo score ≥2 had a significantly higher risk of death or HF hospitalisation (HR 3.44, 95%CI 1.27-9.30, P=0.015, score 0 as reference), driven by HF hospitalisation; in that cohort, adding the MEDIA echo score to the clinical model significantly improved reclassification for the combined endpoint (integrated discrimination improvement 6.2%, P=0.006). Conclusions:The MEDIA echo score significantly predicted the outcome of HFpEF patients in both hospital and ambulatory settings; its use may help refine routine risk-stratification on top of wellestablished prognosticators in stable HFpEF patients.

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“…Nowadays, no echocardiographic prognostic score has had some application in HFpEF, as opposed to HFrEF, for which both echo score and prognostic models have been proposed 23,24 .…”

Section: Comparison With Other Prognostic Scores In Heart Failure Wit...mentioning

confidence: 99%

Validation of the MEDIA echo score for the prognosis of heart failure with preserved ejection fraction

et al. 2022

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“…However, LVEF or LVDF alone is not closely related to the clinical condition and cannot accurately reflect the overall cardiac function of HF patients. The HF echocardiography index (HFEI) is a combination of multiple parameters of echocardiography to evaluate the cardiac function in patients with CHF, which overcomes the subjective factors of New York Heart Association Classification and is more accurate and reliable than the single LVEF [7,8].…”

Section: Introductionmentioning

confidence: 99%

Prognostic value of heart failure echocardiography index in HF patients with preserved, mid-ranged and reduced ejection fraction

Chen

Pei

et al. 2020

BMC Cardiovasc Disord

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Background: To investigate the clinical value of heart failure echocardiography index (HFEI) in evaluating the cardiac function and predicting the prognosis of patients with different types of heart failure (HF). Methods: Four hundred eighty-nine consecutively admitted HF patients were divided into three groups: HF with reduced ejection (HFrEF), HF with mid-range ejection fraction (HFmrEF), and HF with preserved ejection fraction (HFpEF). The baseline characteristics and ultrasound indexes were compared between the three groups. The correlation between HFEI and one-year risk of adverse events was compared by multivariate logistic regression. The clinical value of HFEI and plasma level of NT-proBNP in assessing the prognosis of patients with chronic heart failure (CHF) was analyzed by the receiver operating characteristic (ROC) curve. Results: HFEI in HFrEF was significantly higher than that in HFmrEF and HFpEF. Multivariate regression analysis indicated that HFEI and plasma level of NT-proBNP were independent risk factors for predicting the short-time prognosis of HF patients. The ROC curve indicated that the HFEI cutoff level of 3.5 and the plasma NT-proBNP level of 3000 pg/ml predicted a poor prognosis of CHF patients with a sensitivity of 64% and a specificity of 75% vs. 68 and 65%. Conclusion: HFEI can comprehensively evaluate the overall cardiac function of patients with various types of HF, and may prove to be an important index of assessing the prognosis of HF patients.

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Prognostic role of left ventricular ejection fraction in heart failure: Back to the future?

Ambrosio

Carluccio

2018

International Journal of Cardiology

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Risk stratification of Asian patients with heart failure and reduced ejection fraction: the effectiveness of the Echo Heart Failure Score

Cited by 7 publications

References 16 publications

Validation of the MEDIA echo score for the prognosis of heart failure with preserved ejection fraction

Validation of the MEDIA echo score for the prognosis of heart failure with preserved ejection fraction

Prognostic value of heart failure echocardiography index in HF patients with preserved, mid-ranged and reduced ejection fraction

Prognostic role of left ventricular ejection fraction in heart failure: Back to the future?

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