hat an amazing issue of Pediatric Critical Care Medicine (PCCM) to finish volume 23, 2022. Your December reading could cover three key themes: sepsis and shock, respiratory care and supportive ventilation, and multicenter clinical research groups. There are six articles about sepsis and shock (1−6). I'm using only four of the sepsis/shock themed articles along with one accompanying editorial (7) as my Editor's Choice this month, but I encourage you to read all the articles in this theme. The other two themes are featured in the section below titled PCCM Connections for Readers.