2018
DOI: 10.1007/s41649-018-0056-x
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Risks and benefits of human germline genome editing: An ethical analysis

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Cited by 20 publications
(22 citation statements)
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“…Due to the off-target effect, the use of CRISPR-Cas9 on humans is still considered a risk [1]. Designing an accurate genome editing tool is hence, necessary.…”
Section: Motivationmentioning
confidence: 99%
“…Due to the off-target effect, the use of CRISPR-Cas9 on humans is still considered a risk [1]. Designing an accurate genome editing tool is hence, necessary.…”
Section: Motivationmentioning
confidence: 99%
“…There is also possibilities of gene therapy that aims to insert normal genes into the cells of people who suffer from genetic disorders such as cystic fibrosis, hemophilia or Tay-Sachs diseases. But due to the off target effect, use of CRISPR-Cas9 on human is still considered a risk [2].…”
Section: Motivationmentioning
confidence: 99%
“…10 Long Tails and New Worlds For a health care organization risk manager, how a health care organization or individual practitioners should insure against a tort claim for a technology with unknown, unforeseen risks is simply not clear. 11 There is no current plan in place to insure against descendants of a germline gene-edited person 12 suing an organization or clinician, and there is not enough data about or experience with gene editing to imagine-much less know or foresee-claims risks that future complications could pose. 13 Claims that can foreseeably be made 10, 20, 40, or more years after an original insurance policy has been written are known to risk managers and underwriters as long-tail future claims.…”
Section: Foreseeable Riskmentioning
confidence: 99%