Risks and management of pregnancy in women with epilepsy: a review

Mahajan, Monika

doi:10.18203/2320-1770.ijrcog20181319

Cited by 1 publication

(1 citation statement)

References 21 publications

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“…This may be due to non-adherence to antiepileptic medications. One patient had multiple seizure episodes in second and third trimester; this could be due to change in therapeutic levels of leviteracetam in pregnancy, which ideally needs to be monitored as seen in study by Mahajan et al 8 However, RCOG does not currently recommend routine serum antiepileptic drug monitoring because of lack of its evidence on control of seizures. 7 In previous studies like by Goel et al there was 24.3% incidence of PIH and 2.7% incidence of GDM with epilepsy.…”

Section: Discussionmentioning

confidence: 99%

Fetomaternal outcomes in pregnancy complicated by epilepsy: a retrospective study

Chithra

Dixit

Janu

et al. 2021

Int J Reprod Contracept Obstet Gynecol

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Background: This study is conducted to find out possible course and complications of epilepsy and its treatment in mother and fetus as many women will be anxious regarding this high-risk condition.Methods: This is a retrospective study conducted in department of obstetrics and gynaecology, AIMS Kochi from 2012-2019. Out of a total of 7045 deliveries during that period, we identified 64 patients with epilepsy complicating pregnancy. Antepartum, intrapartum and postpartum details of 57 patients whose data was available in electronic medical records was collected and analysed using SPSS 17 software.Results: In this study we noted that the incidence of epilepsy was 0.009%. the 50% of patients were in 25-30 years age group. More than 98% were on long term antiepileptic drugs. Majority were on monotherapy, most commonly on leviteracetam and were well controlled with monotherapy. The 38.5% had recurrence of seizures during pregnancy, mostly in latter half of pregnancy. Patients with seizure free interval of 9 months prior to pregnancy did not have any further epilepsy episodes. The incidence of other medical and obstetric complications was found to be similar to general population. There was 10% incidence of IUGR and fetal anomaly.Conclusions: The seizures were well controlled with monotherapy and we found that generally pregnancy and delivery is well tolerated and overall neonatal outcomes were good.

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Section: Discussionmentioning

confidence: 99%