Risks and quality-of-life changes in living kidney donors

Chen, C.-H.; Chen, Y.; Chiang, Yang‐Jen; Wu, Cheng-Ta; Chen, H.-W.; Chu, Shih-Ming

doi:10.1016/j.transproceed.2004.08.016

Cited by 26 publications

(21 citation statements)

References 5 publications

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“…Fourteen studies provided minimal to no demographic information or relevant descriptors for their donor participants (29)(30)(31)(32)39,41,55,58,59,69,73,(75)(76)(77). A decision to follow donors prospectively in time was described in 10 studies (32,37,39,52,53,63,65,71,72,77).…”

Section: Methods Appraisalmentioning

confidence: 99%

“…Studies were from 19 countries; most were conducted in the United States (43% of studies) followed by Germany (10%), Canada (6%), India (4%), Sweden (4%), Australia (4%), the Netherlands (4%) and Switzerland (4%). During follow-up, 46 studies assessed the physical health of donors (29)(30)(31)(32)(33)(34)(35)(36)38,(40)(41)(42)(43)(44)(45)(46)(48)(49)(50)(51)(53)(54)(55)(56)(57)(58)(59)(60)(61)(63)(64)(65)(66)(67)(68)(69)(70)(71)(72)(73)(74)(75)(76)(77)(78)(79) and 26 reported that some donors had faced graft failure or recipient death (29,(31)(32)…”

Section: Description Of Studiesmentioning

confidence: 99%

“…The remaining studies contacted previous donors' months to years after nephrectomy, with 20 studies not reporting the average time since donation (29)(30)(31)(32)(33)36,39,41,47,49,55,59,66,(68)(69)(70)(73)(74)(75)(76). The number of donors considered for follow-up was often unreported and thus for some studies, the response rate could not be calculated (37,39,41,52,56,59,64,68,72 (40,44,46,48,50,60,62,63,65,73,78) and five compared their characteristics to responders (40,44,46,50,65).…”

Section: Psychosocial Health Of Live Kidney Donorsmentioning

confidence: 99%

“…The number of donors considered for follow-up was often unreported and thus for some studies, the response rate could not be calculated (37,39,41,52,56,59,64,68,72 (40,44,46,48,50,60,62,63,65,73,78) and five compared their characteristics to responders (40,44,46,50,65).…”

Section: Psychosocial Health Of Live Kidney Donorsmentioning

confidence: 99%

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Psychosocial Health of Living Kidney Donors: A Systematic Review

Clemens

Thiessen‐Philbrook

Parikh

et al. 2006

American Journal of Transplantation

253

213

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Knowledge of the psychosocial benefits and harms faced by living kidney donors is necessary for informed consent and follow-up. We reviewed any English language study where psychosocial function was assessed using questionnaires in 10 or more donors after nephrectomy. We searched MEDLINE, EM-BASE, Web of Science, Psych INFO, Sociological Abstracts and CINAHL databases and reviewed reference lists from 1969 through July 2006. Independently, two reviewers abstracted data on study, donor and control group characteristics, psychosocial measurements and their outcomes. Fifty-one studies examined 5139 donors who were assessed an average of 4 years after nephrectomy. The majority experienced no depression (77-95%) or anxiety (86-94%), with questionnaire scores similar to controls. The majority reported no change or an improved relationship with their recipient (86-100%), spouse (82-98%), family members (83-100%) and nonrecipient children (95-100%). Some experienced an increase in self-esteem. A majority (83-93%) expressed no change in their attractiveness. Although many scored high on quality of life measures, some prospective studies described a decrease after donation. A small proportion of donors had adverse psychosocial outcomes. Most kidney donors experience no change or an improvement in their psychosocial health after donation. Harms may be minimized through careful selection and follow-up.

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Section: Methods Appraisalmentioning

confidence: 99%

Section: Description Of Studiesmentioning

confidence: 99%

Section: Psychosocial Health Of Live Kidney Donorsmentioning

confidence: 99%

Section: Psychosocial Health Of Live Kidney Donorsmentioning

confidence: 99%

See 2 more Smart Citations

Psychosocial Health of Living Kidney Donors: A Systematic Review

Clemens

Thiessen‐Philbrook

Parikh

et al. 2006

American Journal of Transplantation

253

213

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“…Three donors had to be readmitted 1 mo after the operation for aspiration of a purulent subphrenic collection. The most common problem, especially for young donors who cared about their looks, was scar formation [8] . At 1-year followup, prominent hypertrophic scar was observed in about 5% of donors, but no keloid has ever been detected.…”

Section: Resultsmentioning

confidence: 99%

Donor safety in adult living donor liver transplantation using the right lobe: Single center experience in China

Yan²,

Zeng³

et al. 2007

WJG

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AIM:To evaluate the safety of donors in adult living donor liver transplantation (LDLT) using the right lobe in a single liver transplantation center in China. METHODS:We investigated retrospectively 52 living donor liver resections performed from October 2003 to July 2006. All patients were evaluated by blood tests and abdominal CT. The mean donor age was 28.2 ± 7.4 years. Residual liver volume was 42.1% ± 4.7%. Mean operative time was 420 ± 76.2 min; mean ICU stay, less than 36 h; mean hospital stay, 16.4 ± 8.6 d; and mean follow-up period, 6 mo. RESULTS:T h e r e wa s n o m o r t a l i ty. T h e o ve ra l l c o m p l i c a t i o n ra t e wa s 4 0 % ( 2 1 d o n o r s ) . M a j o r c o m p l i c a t i o n s i n c l u d e d b i l i a r y l e a k i n t w o, a n d pneumonia in 2 donors. Minor complications included mild pleural effusion in 12 donors, transient ascites in 6, mild depression in 4, intra-abdominal collections in 2, and wound infections in 1 donor. Residual liver volume did not affect the complication rate. None required reoperation. Return to pre-donation activity occurred within 5-8 wk.CONCLUSION: Right hemi-hepatectomy can be performed safely with minimal risk in cases of careful donor selection. Major complications occurred in only 7.7% of our series.

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Donor perspectives in living kidney transplantation

Rana

Akoh

2010

Dialysis & Transplantation

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OBJECTIVEThe aim of this study was to determine the overall experience of living kidney donors.METHODSAll 80 kidney donors at a teaching hospital between 2003 and 2008 were sent a postal questionnaire to determine the level of satisfaction with the kidney donation process, including post‐operative pain and return to fitness after surgery.RESULTSA total of 56 donors returned the questionnaires. The average loss of earnings in 29 donors was £995.17 6 £297.03. A total of 52 donors (93%) rated their overall experience as excellent or good, 55 donors (98%) had no regrets about donation, and 26 donors (46%) would have considered altruistic donation if they were unable to donate to their intended recipient. Qualitative analysis of responses showed a positive attitude to organ donation, with a willingness to encourage others, a request for chat facilities on the unit's website, and a more regular follow‐up.DISCUSSIONLiving kidney donors were generally satisfied with the organ donation process and likely to recommend it to others. The issue of compensation for loss of earnings must be addressed in order to encourage other potential donors. Perhaps other potential donors withdrawing from the assessment process due to inability to donate to their intended recipient should be counseled about altruistic non‐directed donation.

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Risks and quality-of-life changes in living kidney donors

Cited by 26 publications

References 5 publications

Psychosocial Health of Living Kidney Donors: A Systematic Review

Psychosocial Health of Living Kidney Donors: A Systematic Review

Donor safety in adult living donor liver transplantation using the right lobe: Single center experience in China

Donor perspectives in living kidney transplantation

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