Risks of in-hospital death and hospital length of stay of 7 days or longer among end-stage renal disease patients hospitalized with COVID-19: a retrospective cohort study in five California medical centers

Abstract

Patients with pre-existing chronic health conditions, including End-Stage Renal Disease (ESRD) requiring dialysis, are at high risk for hospitalization with COVID-19. Kidney failure leads to a poorly regulated immune system [1], and susceptibility to infections, which is the second most reported cause of death in the ESRD population.Studies of hospitalized ESRD patients early in the COVID-19 pandemic have reached different conclusions, with some finding that ESRD conveys an independent risk for in-hospital death [2], and others not finding this association [3]. We sought to examine ESRD as an independent risk factor for poor outcomes in individuals hospitalized with

End-stage kidney disease patients with severe coronavirus disease: clinical characteristics, biological data, and mortality in nephrology unit, short communication

“…However, recent studies argue against this finding. In the first recent study, the authors found that without adjustment, ESKD patients hospitalized for COVID-19 had a significantly higher odds of in-hospital death than patients without ESKD, but once comprehensively adjusted, there was no excess risk of death for ESRD patients 10 . In the second study, the authors found that among individuals with COVID-19-positive test result, ESKD patients did not have a higher odd for adverse outcomes (mortality, stroke, shock, intubation, sepsis, pneumonia) compared with matched individuals without ESKD 11 .…”