Risperidone Olanzapine Drug Outcomes studies in Schizophrenia (RODOS) single-center report from 8an international study series

Bille, A.; Andersen, J.

doi:10.1016/s0924-977x(99)80339-3

Cited by 2 publications

(2 citation statements)

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“…There is some evidence that clozapine and other SGAs are more effective and cost‐effective than FGAs for people who demonstrate treatment resistance or intolerance to previous therapy [13–49]. The UK National Institute for Health and Clinical Excellence (NICE) suggests that for people with treatment‐resistant schizophrenia (TRS), clozapine should be introduced at the earliest opportunity [50].…”

Section: Introductionmentioning

confidence: 99%

A Randomized Controlled Trial of the Cost-Utility of Second-Generation Antipsychotics in People with Psychosis and Eligible for Clozapine

et al. 2008

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This study adds to a limited body of evidence comparing clozapine to other SGAs and is the first economic and clinical RCT to compare clozapine to the class of other SGAs using the lower cost of generic clozapine and a pragmatic trial design. Policy decisions by the NICE suggest that additional reasons would be needed to accept clozapine as effective and efficient if it had a high probability of having ICERs more than 35,000 pound per QALY. The results and limitations of the analysis suggest that there is still a need for further economic evaluation of clozapine.

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Section: Introductionmentioning

confidence: 99%

A Randomized Controlled Trial of the Cost-Utility of Second-Generation Antipsychotics in People with Psychosis and Eligible for Clozapine

et al. 2008

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“…33 Several economic evaluations have been published. These have used a range of study designs such as controlled and uncontrolled cohorts 117,126,[129][130][131][132][133][134][135][136][137][138][139][140][141][142] and controlled trials. 73,[143][144][145][146][147][148][149][150][151][152] A large number of modelling studies has been published, based on data from a variety of sources.…”

Section: The Economics Of Schizophreniamentioning

confidence: 99%

Randomised controlled trials of conventional antipsychotic versus new atypical drugs, and new atypical drugs versus clozapine, in people with schizophrenia responding poorly to, or intolerant of, current drug treatment

Lewis

Davies²,

Jones³

et al. 2006

Health Technol Assess

135

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Risperidone Olanzapine Drug Outcomes studies in Schizophrenia (RODOS) single-center report from 8an international study series

Cited by 2 publications

References 0 publications

A Randomized Controlled Trial of the Cost-Utility of Second-Generation Antipsychotics in People with Psychosis and Eligible for Clozapine

A Randomized Controlled Trial of the Cost-Utility of Second-Generation Antipsychotics in People with Psychosis and Eligible for Clozapine

Randomised controlled trials of conventional antipsychotic versus new atypical drugs, and new atypical drugs versus clozapine, in people with schizophrenia responding poorly to, or intolerant of, current drug treatment

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