Rituximab-induced hypogammaglobulinemia in nephrotic syndrome: what is the true burden?

Chan, Eugene Yu-hin

doi:10.1007/s00467-024-06371-z

Pediatr Nephrol

2024

DOI: 10.1007/s00467-024-06371-z

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Rituximab-induced hypogammaglobulinemia in nephrotic syndrome: what is the true burden?

Eugene Yu-hin Chan

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2024

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Childhood idiopathic nephrotic syndrome: recent advancements shaping future guidelines

Chan,

Boyer

2024

Pediatr Nephrol

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Childhood idiopathic nephrotic syndrome is an important pediatric kidney disease associated with significant morbidities and even mortality. Several guidelines have been developed to standardize the terminology and patient care among the pediatric nephrology community. Since the publication of these guidelines, there have been major breakthroughs in the disease management and the understanding of underlying pathogenesis through multi-omics investigations, including the identification of anti-nephrin autoantibodies, genetic susceptibility loci, and the pathogenic role of B cell subsets. In this educational review, we summarize the recent major advancements in idiopathic nephrotic syndrome and attempt to provide potential therapeutic approaches in both steroid-sensitive and steroid-resistant nephrotic syndrome that may shape future guideline development. Graphical abstract

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Childhood idiopathic nephrotic syndrome: recent advancements shaping future guidelines

Chan,

Boyer

2024

Pediatr Nephrol

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An international, multi-center study evaluated rituximab therapy in childhood steroid-resistant nephrotic syndrome

Chan,

Sinha,

et al. 2024

Kidney International

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Rituximab-induced hypogammaglobulinemia in nephrotic syndrome: what is the true burden?

Cited by 2 publications

References 3 publications

Childhood idiopathic nephrotic syndrome: recent advancements shaping future guidelines

Childhood idiopathic nephrotic syndrome: recent advancements shaping future guidelines

An international, multi-center study evaluated rituximab therapy in childhood steroid-resistant nephrotic syndrome

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